Health-related quality of life in psoriatic arthritis: findings and implications

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dc.creatorFelipe A. Moraes
dc.creatorMichael R. R. da Silva
dc.creatorJéssica B. R. dos Santos
dc.creatorFrancisco de Assis Acurcio
dc.creatorAlessandra Maciel Almeida
dc.creatorAdriana Maria Kakehasi
dc.creatorJuliana Alvares Teodoro
dc.date.accessioned2023-07-18T20:31:08Z
dc.date.accessioned2025-09-09T01:23:25Z
dc.date.available2023-07-18T20:31:08Z
dc.date.issued2021
dc.identifier.doihttps://doi.org/10.1016/j.vhri.2021.06.003
dc.identifier.issn2212-1102
dc.identifier.urihttps://hdl.handle.net/1843/56641
dc.languagepor
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofValue in Health Regional Issues
dc.rightsAcesso Aberto
dc.subjectArtrite
dc.subjectQualidade de vida
dc.subject.otherCross-sectional study
dc.subject.otherHealth system
dc.subject.otherPsoriatic arthritis
dc.subject.otherQuality of life
dc.titleHealth-related quality of life in psoriatic arthritis: findings and implications
dc.typeArtigo de periódico
local.citation.epage141
local.citation.spage135
local.citation.volume26
local.description.resumoObjectives: To assess the quality of life (QOL) and its associated factors in patients with psoriatic arthritis (PsA) who would start treatment with biologic drugs at the Brazilian Unified Health System. Methods: A cross-sectional study was performed at a single center pharmacy in Belo Horizonte, State of Minas Gerais, Brazil. EQ-5D was used to assess the patients’ QOL. The functional status was assessed using the Health Assessment Questionnaire Disability Index, whereas disease activity was evaluated through the Bath Ankylosing Spondylitis Disease Activity Index and the Clinical Disease Activity Index. Simple and multiple linear regression analyses were performed to assess the factors associated with QOL. Results: A total of 212 patients with PsA were included, of which 185 (87.3%) reported having some pain/discomfort, and 148 (69.8%) presented some level of anxiety/depression. Patients with PsA had a mean QOL score of 0.651 (SD 0.12) with a sig nificant reduction in female patients, concomitant use of nonsteroidal anti-inflammatory drugs, comorbidity, and worse clinical and functional status. Poor QOL was associated with worse functional status by the Health Assessment Questionnaire-Disability Index, disease activity by the Bath Ankylosing Spondylitis Disease Activity Index, and with diagnoses of osteoporosis, hypothyroidism, and depression. Conclusion: PsA and its associated comorbidities negatively affect the QOL, evidencing the need for a comprehensive and effective clinical approach.
local.identifier.orcidhttps://orcid.org/0000-0002-5880-5261
local.identifier.orcidhttps://orcid.org/0000-0003-0138-9401
local.identifier.orcidhttps://orcid.org/0000-0001-9411-7493
local.identifier.orcidhttps://orcid.org/0000-0002-0210-0721
local.publisher.countryBrasil
local.publisher.departmentFAR - DEPARTAMENTO DE FARMÁCIA SOCIAL
local.publisher.departmentMED - DEPARTAMENTO DE APARELHO LOCOMOTOR
local.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S2212109921000935#:~:text=When%20compared%20with%20the%20general,and%20significantly%20increased%20mortality%20rate.

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