Clinical characteristics and outcomes of patients hospitalized with COVID-19 in Brazil: Results from the Brazilian COVID-19 registry

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dc.creatorMariana de Braga Lima Carvalho Canesso
dc.creatorMatheus Carvalho Alves Nogueira
dc.creatorMeire Pereira de Figueiredo
dc.creatorMilton Henriques Guimarães Junior
dc.creatorMychelle Stefany Santos Almeida
dc.creatorMônica Aparecida de Paula de Sordi
dc.creatorNatália da Cunha Severino Sampaio
dc.creatorThaís L.s. Sales
dc.creatorNeimy Ramos de Oliveira
dc.creatorPaulo Tarso Lima Vianna
dc.creatorPedro Guido Soares Andrade
dc.creatorPedro Ledic Assaf
dc.creatorRafael Fusaro Aguiar Oliveira
dc.creatorRafael Lima Rodrigues de Carvalho
dc.creatorRafaela Dos Santos Charão de Almeida
dc.creatorRaphael Castro Martins
dc.creatorReginaldo Aparecido Valacio
dc.creatorRicardo Bertoglio Cardoso
dc.creatorKaren b. Ruschel
dc.creatorRicardo Braga Coelho
dc.creatorRoberta Pozza
dc.creatorRodolfo Lucas Silva Mourato
dc.creatorRodrigo Costa Pereira Vieira
dc.creatorRoger Mendes de Abreu
dc.creatorRufino de Freitas Silva
dc.creatorSaionara Cristina Francisco
dc.creatorSilvana Mangeon Mereilles Guimarães
dc.creatorSilvia Ferreira Araújo
dc.creatorTalita Fischer Oliveira
dc.creatorKarina P.m.p. Martins
dc.creatorTatiana de Vargas
dc.creatorTatiani Oliveira Fereguetti
dc.creatorThalita Martins Lage
dc.creatorThulio Henrique Oliveira Diniz
dc.creatorVeridiana Baldon Dos Santos
dc.creatorMilena S.marcolino
dc.creatorAna Paula B.s. Etges
dc.creatorIsrael Molina
dc.creatorCarisi a. Polanczyk
dc.creatorAlexandre Vargas Schwarbold
dc.creatorAmanda de Oliveira Maurílio
dc.creatorAna Lara Rodrigues Monteiro de Barros
dc.creatorAna Luiza Bahia Alves Scotton
dc.creatorAlfonso j. Rodríguez-morales
dc.creatorAnderson Lacerda Dos Reis
dc.creatorAndré Soares Moura Costa
dc.creatorPatricia k. Ziegelmann
dc.creatorArgenil José Assis de Oliveira
dc.creatorBárbara Lopes Farace
dc.creatorCarla Thais Cândida Alves da Silva
dc.creatorCarolina Marques Ramos
dc.creatorChristiane Corrêa Rodrigues Cimini
dc.creatorCíntia Alcantara de Carvalho
dc.creatorDaniel Vitório Silveira
dc.creatorDaniela Ponce
dc.creatorEmanuele Marianne Souza Kroger
dc.creatorEuler Roberto Fernandes Manenti
dc.creatorMaira V.r. Souza-silva
dc.creatorFernanda Barbosa Lucas
dc.creatorFernanda D'athayde Rodrigues
dc.creatorFernando Anschau
dc.creatorFernando Antonio Botoni
dc.creatorFrederico Bartolazzi
dc.creatorGabriela Petry Crestani
dc.creatorGuilherme Fagundes Nascimento
dc.creatorHelena Carolina Noal
dc.creatorHelena Duani
dc.creatorHeloisa Reniers Vianna
dc.creatorI.j.b. Nascimento
dc.creatorHenrique Cerqueira Guimarães
dc.creatorJoice Coutinho de Alvarenga
dc.creatorJúlia Drumond Parreiras de Morais
dc.creatorJuliana Machado Rugolo
dc.creatorLara Monalyza Gonçalves Franco
dc.creatorLeila Beltrami Moreira
dc.creatorLeonardo Seixas de Oliveira
dc.creatorLílian Santos Pinheiro
dc.creatorLiliane Souto Pacheco
dc.creatorLuciane Kopittke
dc.creatorLuana m. Oliveira
dc.creatorLuciano de Souza Viana
dc.creatorLuis Cesar Souto de Moura
dc.creatorLuisa Elem Almeida Santos
dc.creatorMáderson Alvares de Souza Cabral
dc.creatorMaíra Dias Souza
dc.creatorMarcela Gonçalves Trindade Tofani
dc.creatorMarconi Franco da Silveira
dc.creatorMarcus Vinicius de Melo Andrade
dc.creatorMaria Angélica Pires Ferreira
dc.creatorMaria Aparecida Camargos Bicalho
dc.creatorLuanna s. Monteiro
dc.creatorMaria Auxiliadora Parreiras Martins
dc.creatorMaria Clara Pontello Barbosa Lima
dc.creatorMariana Balbinot Borges
dc.date.accessioned2023-08-07T18:50:42Z
dc.date.accessioned2025-09-09T00:23:46Z
dc.date.available2023-08-07T18:50:42Z
dc.date.issued2021
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1016/j.ijid.2021.01.019
dc.identifier.issn1201-9712
dc.identifier.urihttps://hdl.handle.net/1843/57559
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofInternational Journal of Infectious Diseases
dc.rightsAcesso Aberto
dc.subjectCOVID-19
dc.subjectSARS-CoV-2
dc.subjectHospitalizações
dc.subjectMortalidade
dc.subjectProgressão Da Doença
dc.subject.otherCOVID-19
dc.subject.otherSARS-CoV-2
dc.subject.otherHospitalizations
dc.subject.otherMortality
dc.subject.otherDisease progression
dc.titleClinical characteristics and outcomes of patients hospitalized with COVID-19 in Brazil: Results from the Brazilian COVID-19 registry
dc.typeArtigo de periódico
local.citation.epage310
local.citation.spage300
local.description.resumoObjectives: To describe the clinical characteristics, laboratory results, imaging findings, and in-hospital outcomes of COVID-19 patients admitted to Brazilian hospitals.Methods: A cohort study of laboratory-confirmed COVID-19 patients who were hospitalized from March 2020 to September 2020 in 25 hospitals. Data were collected from medical records using Research Electronic Data Capture (REDCap) tools. A multivariate Poisson regression model was used to assess the risk factors for in-hospital mortality. Results: For a total of 2,054 patients (52.6% male; median age of 58 years), the in-hospital mortality was 22.0%; this rose to 47.6% for those treated in the intensive care unit (ICU). Hypertension (52.9%), diabetes(29.2%), and obesity (17.2%) were the most prevalent comorbidities. Overall, 32.5% required invasive mechanical ventilation, and 12.1% required kidney replacement therapy. Septic shock was observed in 15.0%, nosocomial infection in 13.1%, thromboembolism in 4.1%, and acute heart failure in 3.6%. Age >= 65 years, chronic kidney disease, hypertension, C-reactive protein 100 mg/dL, platelet count < 100 =109/L, oxygen saturation < 90%, the need for supplemental oxygen, and invasive mechanical ventilation at admission were independently associated with a higher risk of in-hospital mortality. The overall use of antimicrobials was 87.9%. Conclusions: This study reveals the characteristics and in-hospital outcomes of hospitalized patients with confirmed COVID-19 in Brazil. Certain easily assessed parameters at hospital admission were independently associated with a higher risk of death.
local.identifier.orcidhttps://orcid.org/0000-0001-9345-018X
local.publisher.countryBrasil
local.publisher.departmentFAR - DEPARTAMENTO DE PRODUTOS FARMACÊUTICOS
local.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S1201971221000308?via%3Dihub

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