Odontogenic carcinosarcoma: a systematic review

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dc.creatorLauren Frenzel Schuch
dc.creatorJosé Alcides Almeida de Arruda
dc.creatorLeni Verônica de Oliveira Silva
dc.creatorLucas Guimarães Abreu
dc.creatorTarcília Aparecida da Silva
dc.creatorRicardo Alves de Mesquita
dc.date.accessioned2025-04-03T20:01:11Z
dc.date.accessioned2025-09-08T23:27:53Z
dc.date.available2025-04-03T20:01:11Z
dc.date.issued2018-10
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1016/j.oraloncology.2018.08.017
dc.identifier.issn1879-0593
dc.identifier.urihttps://hdl.handle.net/1843/81285
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofOral Oncology
dc.rightsAcesso Restrito
dc.subjectCarcinosarcoma
dc.subjectClinical study
dc.subjectHead and neck neoplasms
dc.subjectNeoplasms
dc.subjectOdontogenic tumors
dc.subjectMouth neoplasms
dc.subjectRecurrence
dc.subjectSurgical oncology
dc.subjectMandible
dc.subjectDiagnosis, oral
dc.subjectNeoplasm metastasis
dc.subjectDeath
dc.subject.otherCarcinosarcoma
dc.subject.otherClinical features
dc.subject.otherHead and neck cancer
dc.subject.otherNeoplasms
dc.subject.otherOdontogenic tumors
dc.subject.otherOral cancer
dc.subject.otherOral oncology
dc.subject.otherRecurrence rate
dc.titleOdontogenic carcinosarcoma: a systematic review
dc.typeArtigo de periódico
local.citation.epage59
local.citation.spage52
local.citation.volume85
local.description.resumoThe aim of this study was to integrate the available data published on odontogenic carcinosarcoma into a comprehensive analysis of their features, treatment and recurrence. An electronic search with no publication date or language restriction was undertaken in March 2018 in the following databases: Medline Ovid, PubMed, Web of Science, Scopus and LILACS. Eligibility criteria included publications having enough clinical, imaginological and histopathological information to confirm a definite diagnosis of the neoplasm. Data were evaluated descriptively and statistically using the MedCalc software. The Kaplan-Meier method was used for survival analysis. The systematic review detected nine articles from eight countries. Six cases with no age predilection occurred in male individuals complaining of painful swelling in the posterior mandible. Radiographically, the lesions were large, with expansive radiolucency and with ill-defined borders and seven cases were associated with preexisting odontogenic lesions. Radical surgery was the treatment of choice in the majority of cases. Recurrences (n = 6), metastasis (n = 4) and death (n = 4) were frequently observed in many cases. Odontogenic carcinosarcoma is a very aggressive neoplasm with a poor prognosis. This study provides knowledge that could help surgeons, oncologists, otorhinolaryngologists and oral maxillofacial pathologists with the diagnosis and management of these lesions.
local.identifier.orcidhttps://orcid.org/0000-0002-0993-936X
local.identifier.orcidhttps://orcid.org/0000-0002-6599-3950
local.identifier.orcidhttps://orcid.org/0000-0003-0336-9359
local.identifier.orcidhttps://orcid.org/0000-0003-2258-8071
local.identifier.orcidhttps://orcid.org/0000-0001-9623-7835
local.identifier.orcidhttps://orcid.org/0000-0003-3207-4007
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S1368837518303051?via%3Dihub

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