Reduction in pregnancies and litters in mice couples with splenectomized male

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dc.creatorDalton Munizsantos
dc.creatorGisele Araújo Pereira
dc.creatorKelly Renata Sabino
dc.creatorAndy Petroianu
dc.date.accessioned2024-01-23T18:21:45Z
dc.date.accessioned2025-09-09T01:32:13Z
dc.date.available2024-01-23T18:21:45Z
dc.date.issued2021
dc.format.mimetypepdf
dc.identifier.doi10.1590/acb360201
dc.identifier.issn16782674
dc.identifier.urihttps://hdl.handle.net/1843/63262
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofActa Cirúrgica Brasileira
dc.rightsAcesso Aberto
dc.subjectSpleen
dc.subjectReproduction
dc.subjectSplenectomy
dc.subjectSexual disfunction
dc.subjectFertility
dc.subject.otherSpleen
dc.subject.otherSexual disfunction
dc.subject.otherSplenectomy
dc.subject.otherFertility
dc.subject.otherReproduction
dc.titleReduction in pregnancies and litters in mice couples with splenectomized male
dc.typeArtigo de periódico
local.citation.epage5
local.citation.issue2
local.citation.spage1
local.citation.volume36
local.description.resumoPurpose: The spleen is relevant in blood purification, hematopoiesis, metabolism, and immune response to antigens, in addition to the storage and control on the release of metals and amino acids. Its functions concerning reproduction characteristics are still unknown. The objective was to study the influence of splenectomies on reproduction. Methods: This study analyzed 25 mice couples, distributed into five groups: group 1 – control, no surgery: group 2 – control, submitted to laparotomy and laparorrhaphy only; group 3 splenectomy in male mice; group 4 – splenectomy in female mice; group 5 – splenectomy in male and female mice. The animals were studied as regards the number of gestations and offspring generated in each gestation. Results: A decrease in both the number of gestations and the number of offspring was verified in the male mice that had received a splenectomy when coupled with normal female mice. It is important to emphasize lower reproduction level when paired asplenic males with normal females, otherwise, the couples in which both mice had been splenectomized did not present change in the reproduction pattern. Conclusion: A reduction in the number of pregnancies and litters occurs in mice couples when the male mice were previously splenectomized.
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE CIRURGIA
local.publisher.initialsUFMG
local.url.externahttps://doi.org/10.1590/ACB360201

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