Impact of COVID-19 pandemic on serum 25-hydroxyvitamin D levels in brazilian patients

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dc.creatorGabriel Pissonati Bretz
dc.creatorJoão Rodrigo Campos
dc.creatorAdriano Alonso Veloso
dc.creatorKarina Braga Gomes Borges
dc.creatorAdriano Basques Fernandes
dc.date.accessioned2025-02-03T20:56:50Z
dc.date.accessioned2025-09-09T01:32:07Z
dc.date.available2025-02-03T20:56:50Z
dc.date.issued2023-10-07
dc.format.mimetypepdf
dc.identifier.doidoi: 10.21037/jlpm-23-35
dc.identifier.issn2519-9005
dc.identifier.urihttps://hdl.handle.net/1843/79616
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJournal of Laboratory and Precision Medicine
dc.rightsAcesso Aberto
dc.subjectCOVID-19 (Doença)
dc.subjectDistanciamento social (Saúde pública)
dc.subjectPandemias
dc.subjectSaúde pública
dc.subject.other25-hydroxyvitamin D (25OH-D)
dc.subject.otherCoronavirus disease 2019 (COVID-19)
dc.subject.otherLockdown
dc.subject.otherSocial distancing
dc.titleImpact of COVID-19 pandemic on serum 25-hydroxyvitamin D levels in brazilian patients
dc.typeArtigo de periódico
local.citation.volume8
local.description.resumoGovernmental actions and public health recommendations during the coronavirus disease 2019 (COVID-19) pandemic resulted in several restrictions on daily living, including social distancing. The impact of these long-term restrictions on health behaviors and lifestyles are unclear, but it could be related to vitamin D (VitD) deficiency. This study aimed to compare VitD levels in patients in pre-pandemic (PP) period and during the most important isolation period in pandemic (DP). We investigated 363,158 results of 25-hydroxyvitamin D (25OH-D) levels from individuals who underwent health checks. The data was obtained from medical records during 2018–2019 (PP); and those results obtained from 2020 to 2021 (DP). 25OH-D levels were measured using a chemiluminescent assay (Siemens®). R software was used to statistical analysis and P value <0.05 was considered significant. 25OH-D levels were compared also regarding age ranges (<18, 18–64 and ≥65 years old) and sex of the individuals. The men group presented higher 25OH-D levels than women only in PP period. During the PP period, individuals <18 years old also showed higher 25OH-D levels. All age groups presented lower 25OH-D levels in DP period, however, the greatest reduction was observed in the group <18 years old. VitD evaluation and supplementation should be considered for overall population submitted to home confinement and social distancing due to COVID-19.
local.identifier.orcidhttps://orcid.org/0000-0002-6870-2063
local.publisher.countryBrasil
local.publisher.departmentFAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICAS
local.publisher.initialsUFMG
local.url.externahttps://jlpm.amegroups.org/article/view/8154/html

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