Endoscopic submucosal dissection with circumferential incision versus tunneling method for treatment of superficial esophageal cancer

Página do item simplificado
dc.creatorTarso Magno Leiteribeiro
dc.creatorVitor Nunes Arantes
dc.creatorJonas Augusto Ramos
dc.creatorPeter v Draganov
dc.creatorDennis Yang
dc.creatorRoberto Gardone Guimarães
dc.date.accessioned2024-01-08T22:44:44Z
dc.date.accessioned2025-09-09T00:08:21Z
dc.date.available2024-01-08T22:44:44Z
dc.date.issued2021
dc.format.mimetypepdf
dc.identifier.doi10.1590/s0004-2803.202100000-35
dc.identifier.issn16784219
dc.identifier.urihttps://hdl.handle.net/1843/62499
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofArquivos de Gastroenterologia
dc.rightsAcesso Aberto
dc.subjectEndoscopic Mucosal Resection
dc.subjectEsophageal Neoplasms
dc.subjectNeoplasms, Squamous Cell
dc.subjectBarrett Esophagus
dc.subject.otherEndoscopic Mucosal Resection
dc.subject.otherSuperficial esophageal neoplasm
dc.subject.otherEsophageal Neoplasms
dc.subject.otherNeoplasms, Squamous Cell
dc.titleEndoscopic submucosal dissection with circumferential incision versus tunneling method for treatment of superficial esophageal cancer
dc.typeArtigo de periódico
local.citation.epage201
local.citation.issue2
local.citation.spage195
local.citation.volume58
local.description.resumoBackground – Endoscopic submucosal dissection (ESD) of esophageal superficial neoplasm is associated with a high en bloc R0 resection rate and low recurrence. Objective – We aim to compare the performance and clinical outcomes of ESD via ESD after circumferential incision (ESD-C) versus submucosal tunneling (ESD-T). Methods – Single-center retrospective analysis of all consecutive patients who underwent ESD for superficial esophageal cancer, between 2009 and 2018. ESD-T was defined as the technique of making the mucosal incisions followed by submucosal tunneling in the oral to anal direction. ESD-C consisted of completing a circumferential incision followed by ESD. Main study outcomes included en bloc and R0 resection rates. Secondary outcomes included procedural characteristics, curative resection rate, local recurrence and adverse events. Results – A total of 65 procedures (23 ESD-T and 42 ESD-C) were performed for ESCC (40; 61.5%) and BE-neoplasia (25; 38.5%). There were no statistically significant differences between patients who underwent ESD-T versus ESD-C in en bloc (91.3% vs 100%, P=0.12), R0 (65.2% vs 78.6%, P=0.24), curative resection rates (65.2% vs 73.8%, P=0.47) and mean procedure time (118.7 min with vs 102.4 min, P=0.35). Adverse events for ESD-T and ESD-C were as follows: bleeding (0 versus 2.4%; P=0.53), perforation (4.3% vs 0; P=0.61), esophageal stricture (8.7% versus 9.5%; P=0.31). Local recurrence was encountered in 8.7% after ESD-T and 2.4% after ESD-C (P=0.28) at a mean follow-up of 8 and 2.75 years, respectively (P=0.001). Conclusion:– ESD-T and ESD-C appear to be equally effective with similar safety profiles for the management of superficial esophageal neoplasms
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE CIRURGIA
local.publisher.initialsUFMG
local.url.externahttps://doi.org/10.1590/S0004-2803.202100000-35

Arquivos

Pacote original

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
Endoscopic submucosal dissection with pdfa.pdf
Tamanho:
800.87 KB
Formato:
Adobe Portable Document Format
Baixar

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG