Direct oral anticoagulants in oral surgery: a prospective cohort

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dc.creatorAmanda Leal Rocha
dc.creatorSicilia Rezende de Oliveira
dc.creatorAlessandra Figueiredo de Souza
dc.creatorDenise Vieira Travassos
dc.creatorLucas Guimarães Abreu
dc.creatorDaniel Dias Ribeiro
dc.creatorTarcília Aparecida da Silva
dc.date.accessioned2025-04-28T19:28:33Z
dc.date.accessioned2025-09-09T00:14:22Z
dc.date.available2025-04-28T19:28:33Z
dc.date.issued2020-12
dc.identifier.doihttps://doi.org/10.23736/S0026-4970.20.04389-7
dc.identifier.issn1827-174X
dc.identifier.urihttps://hdl.handle.net/1843/81934
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofEdizioni minerva medica
dc.rightsAcesso Restrito
dc.subjectHemorrhage
dc.subjectAnticoagulants
dc.subjectOral surgical procedures
dc.subjectTooth extraction
dc.subjectPostoperative hemorrhage
dc.subjectEvaluation study
dc.subject.otherAnticoagulants
dc.subject.otherOral surgical procedures
dc.subject.otherTooth extraction
dc.subject.otherPostoperative hemorrhage
dc.titleDirect oral anticoagulants in oral surgery: a prospective cohort
dc.typeArtigo de periódico
local.citation.epage393
local.citation.issue6
local.citation.spage384
local.citation.volume69
local.description.resumoBACKGROUND: Quantitative assessment of bleeding in dental extractions is rarely reported in the literature. The assessment of bleeding might provide additional evidence to predict and minimize postoperative outcomes. The aim of this study was to evaluate the pattern of bleeding in individuals taking direct oral anticoagulants (DOACs) submitted to dental extractions. METHODS: Intraoperative bleeding was evaluated by using total collected bleeding corrected by absorbance reading (dental bleeding score). To monitoring bleeding episodes from the day of surgery, this cohort was followed up until the seventh postoperative day. RESULTS: Forty-five procedures were performed in three comparative groups, patients under DOACs, individuals taking vitamin K antagonists (VKAs) and without anticoagulant therapy. No bleeding events were observed in procedures carried out in individuals of the DOAC group. Additional hemostatic measures were required in two procedures in the VKA group and one in the non-anticoagulated group. The dental bleeding scores obtained for the DOAC and VKA groups were similar. CONCLUSIONS: Our data suggest that the DOAC therapy did not result in increased bleeding outcomes in this sample.
local.identifier.orcidhttps://orcid.org/0000-0002-4362-7386
local.identifier.orcidhttps://orcid.org/0000-0002-8164-2122
local.identifier.orcidhttps://orcid.org/0000-0003-2084-9557
local.identifier.orcidhttps://orcid.org/0000-0001-6923-9229
local.identifier.orcidhttps://orcid.org/0000-0003-2258-8071
local.identifier.orcidhttps://orcid.org/0000-0001-9623-7835
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA SOCIAL E PREVENTIVA
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA
local.publisher.departmentMEDICINA - FACULDADE DE MEDICINA
local.publisher.initialsUFMG
local.url.externahttps://pubmed.ncbi.nlm.nih.gov/32698567/

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