Mortality predictors after liver transplant in the intensive care unit

dc.creatorAna Paula Ragonete Dos Anjos Agostini
dc.creatorIlka de Fátima Santana Ferreira Boin
dc.creatorRodrigo Marques Tonella
dc.creatorAline Maria Heidemann Santos
dc.creatorAntonio Luis Eiras Falcão
dc.creatorClaudinéia Muterle Logato
dc.creatorLígia dos Santos Roceto Ratti
dc.creatorLuciana Castilho de Figueiredo
dc.creatorLuíz Cláudio Martins
dc.date.accessioned2023-01-03T16:51:56Z
dc.date.accessioned2025-09-09T00:47:33Z
dc.date.available2023-01-03T16:51:56Z
dc.date.issued2018-06
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1016/j.transproceed.2018.02.087
dc.identifier.issn1873-2623
dc.identifier.urihttps://hdl.handle.net/1843/48591
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofTransplantation Proceedings
dc.rightsAcesso Aberto
dc.subjectTransplante de fígado
dc.subjectTransplante de fígado / mortalidade
dc.subjectUnidade de terapia intensiva
dc.titleMortality predictors after liver transplant in the intensive care unit
dc.typeArtigo de periódico
local.citation.epage1427
local.citation.issue5
local.citation.spage1424
local.citation.volume50
local.description.resumoBackground: The goal of this study was to evaluate the predictive factors of mortality in patients after liver transplantation in an intensive care unit from the University Hospital. Methods: This observational study was conducted by using a database analysis of University Hospital. The sample consisted of patients after liver transplantation registered in the database. The study variables of Sequential Organ Failure Assessment score, Acute Physiology and Chronic Health Disease Classification II (APACHE II), Model for End-Stage Liver Disease, and Child-Pugh scores, and the days of hospitalization in intensive care unit, mechanical ventilation time, and reintubation rate, were correlated. Statistical analysis was performed by using the χ2 test or Fisher exact test, the Mann-Whitney test, and logistic regression analysis. Results: Fifty-eight individuals were analyzed. In the death group, the days of hospitalization in the intensive care unit were within 12 ± 14 days, the time of mechanical ventilation was 180 ± 148 hours, the APACHE II value was 17.6 ± 7.3, the Sequential Organ Failure Assessment score was 8.2 ± 2.7, and reintubation was 40%. In the multivariate regression, the predictive indexes of mortality were the mortality given by APACHE II (odds ratio, 1.1; CI, 1.03–1.17; P = .004), mechanical ventilation time (odds ratio, 1.02; CI, 1.01–1.04; P = .001), and reintubation (odds ratio, 9.06; CI, 1.83–44.9; P = .007). An increase of 1 unit in APACHE II mortality increases the risk of death by 10.2%, and each hour of mechanical ventilation increases the risk of death by 2.6%. Conclusions: The time of mechanical ventilation, orotracheal reintubation, and the mortality given by APACHE II were the variables that best predicted death in this study.
local.identifier.orcidhttps://orcid.org/0000-0002-1165-2149
local.identifier.orcidhttps://orcid.org/0000-0001-5363-0717
local.identifier.orcidhttp://orcid.org/0000-0001-9989-4160
local.identifier.orcidhttp://orcid.org/0000-0003-0949-5516
local.identifier.orcidhttps://orcid.org/0000-0002-2920-2162
local.publisher.countryBrasil
local.publisher.departmentEEF - DEPARTAMENTO DE FISIOTERAPIA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S0041134518302549?via%3Dihub

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