Photoprotective activity and increase of SPF in sunscreen formulation using lyophilized red propolis extracts from Alagoas

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dc.creatorWanessa da Silva de Almeida
dc.creatorGustavo Henrique Bianco de Souza
dc.creatorKatia Michelle Freitas
dc.creatorOrlando Davi Henrique dos Santos
dc.creatorLucas Resende Dutra Souza
dc.creatorViviane Martins Rebello dos Santos
dc.creatorAmanda dos Santos Antunes
dc.creatorRicardo Gonçalves Penido
dc.creatorHelen S. da G. Correa
dc.creatorAndréa Mendes do Nascimento
dc.creatorAngela Leão Andrade
dc.creatorVagner Rodrigues Santos
dc.creatorThiago Cazati
dc.creatorTatiane Roquete Amparo
dc.date.accessioned2025-08-19T19:39:23Z
dc.date.accessioned2025-09-08T23:16:04Z
dc.date.available2025-08-19T19:39:23Z
dc.date.issued2019-08-26
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1016/j.bjp.2019.02.003
dc.identifier.issn1981-528X
dc.identifier.urihttps://hdl.handle.net/1843/84431
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofRevista Brasileira de Farmacognosia
dc.rightsAcesso Aberto
dc.subjectSun protection factor
dc.subjectAntioxidants
dc.subjectAnti-Inflammatory agents
dc.subject.otherSun protection factor
dc.subject.otherRed propolis
dc.subject.otherFilter UVA-UVB
dc.subject.otherTotal phenolics
dc.subject.otherHET-CAM test
dc.subject.otherAntioxidant activity
dc.titlePhotoprotective activity and increase of SPF in sunscreen formulation using lyophilized red propolis extracts from Alagoas
dc.typeArtigo de periódico
local.citation.epage8
local.citation.issue3
local.citation.spage1
local.citation.volume29
local.description.resumoThe excessive sun exposure, coupled with lack of sun protection represents one of the biggest risks to the occurrence of skin cancer and photoaging. Recent strategies for photoprotection have included the incorporation of natural antioxidant and anti-inflammatory compounds, into sunscreens, and the oral administration of natural antioxidant extracts. In this work, we use Brazilian red propolis extract because its antioxidant and anti-inflammatory activities. The aim of this work was to evaluate the sun protection factor and antioxidant activity of different hydroalcoholic extracts of red propolis (70% and 75%) prepared from lyophilized red propolis at room and high temperatures. The sun protection factor in vitro was determined by a spectrophotometric method developed by Mansur. The hydroalcoholic extracts of red propolis incorporated with Filter UVA-UVB 5% Gel Permulem TR-1 presented absorption in the UVB region. Also, the in vitro capacity of the hydroalcoholic extracts of red propolis to increase photoprotective activity of Filter UVA-UVB 5% Gel was evaluated. The hydroalcoholic extracts of red propolis incorporated presented higher values of sun protection factor and showed synergism in the photoprotective activity of Filter UVA-UVB 5% Gel Permulem TR-1. The antioxidant activity and sun protection factor are correlated with total phenolics content of the extracts and the hydroalcoholic extract of red propolis 75% at room temperature was choosen. The formulation developed with Filter UVA-UVB 5% Gel Permulem TR-1 with this hydroalcoholic extract of red propolis showed safe to be applied on the skin according HET-CAM test. Suggests indication of hydroalcoholic extract of red propolis (75% – room temperature) associated to photoprotective formulations for use in photoprotective products.
local.identifier.orcidhttps://orcid.org/0000-0002-5164-8603
local.identifier.orcidhttps://orcid.org/0000-0001-9990-3995
local.identifier.orcidhttps://orcid.org/0000-0003-4964-8273
local.identifier.orcidhttps://orcid.org/0000-0001-8853-4266
local.identifier.orcidhttps://orcid.org/0000-0002-3753-1409
local.identifier.orcidhttps://orcid.org/0000-0002-0888-5072
local.identifier.orcidhttps://orcid.org/0000-0002-5370-4867
local.identifier.orcidhttps://orcid.org/0000-0002-3769-9658
local.identifier.orcidhttps://orcid.org/0000-0002-1548-3274
local.identifier.orcidhttps://orcid.org/0000-0002-6426-7113
local.identifier.orcidhttps://orcid.org/0000-0002-4025-879X
local.identifier.orcidhttps://orcid.org/0000-0002-8904-6990
local.identifier.orcidhttps://orcid.org/0000-0003-2408-3448
local.identifier.orcidhttps://orcid.org/0000-0002-0144-9518
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://www.scielo.br/j/rbfar/a/sxxddrxkfnhyg4NQqNGcsWN/?lang=en

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