Zika virus challenges for neuropsychiatry

dc.creatorAna Cristina Simões e Silva
dc.creatorJanaina Matos Moreira
dc.creatorRoberta Maia Castro Rmanelli
dc.creatorAntônio Lúcio Teixeira
dc.date.accessioned2023-08-18T20:53:39Z
dc.date.accessioned2025-09-08T23:01:10Z
dc.date.available2023-08-18T20:53:39Z
dc.date.issued2016
dc.format.mimetypepdf
dc.identifier.doi10.2147/NDT.S113037
dc.identifier.issn11782021
dc.identifier.urihttps://hdl.handle.net/1843/57951
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofNeuropsychiatric Disease and Treatment
dc.rightsAcesso Aberto
dc.subjectZika virus
dc.subjectSíndrome de Guillain-Barré
dc.subjectMicrocefalia
dc.subjectTranstornos do Neurodesenvolvimento
dc.subject.otherZika virus
dc.subject.otherMicrocephaly
dc.subject.otherGuillain-Barré syndrome
dc.subject.otherNeurodevelopmental disorders
dc.titleZika virus challenges for neuropsychiatry
dc.typeArtigo de periódico
local.citation.epage1760
local.citation.spage1747
local.citation.volume14
local.description.resumoBefore 2007, Zika virus (ZIKV) was generally considered as an arbovirus of low clinical relevance, causing a mild self-limiting febrile illness in tropical Africa and Southeast Asia. Currently, a large, ongoing outbreak of ZIKV that started in Brazil in 2015 is spreading across the Americas. Virus infection during pregnancy has been potentially linked to congenital malformations, including microcephaly. In addition to congenital malformations, a temporal association between ZIKV infection and an increase in cases of Guillain–Barré syndrome is currently being observed in several countries. The mechanisms underlying these neurological complications are still unknown. Emerging evidence, mainly from in vitro studies, suggests that ZIKV may have direct effects on neuronal cells. The aim of this study was to critically review the literature available regarding the neurobiology of ZIKV and its potential neuropsychiatric manifestations.
local.identifier.orcidhttps://orcid.org/0000-0001-5369-9175
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE PEDIATRIA
local.publisher.initialsUFMG
local.url.externahttps://www.dovepress.com/zika-virus-challenges-for-neuropsychiatry-peer-reviewed-fulltext-article-NDT

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