Synthesis of potential anti-trypanosoma cruzi azole-naftifine analogues by azide-alkyne click reaction

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dc.creatorCarlos Henrique Callegario Zacchi
dc.creatorStephanie Souto Maior Federighi
dc.creatorFernanda Ramos Gadelha
dc.creatorFelipe Terra Martins
dc.creatorRosemeire Brondi Alves
dc.creatorÂngelo de Fátima
dc.date.accessioned2024-09-20T18:54:57Z
dc.date.accessioned2025-09-08T23:45:31Z
dc.date.available2024-09-20T18:54:57Z
dc.date.issued2018
dc.identifier.doihttps://doi.org/10.1016/j.mencom.2018.03.029
dc.identifier.issn0959-9436
dc.identifier.urihttps://hdl.handle.net/1843/76753
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofMendeleev Communications
dc.rightsAcesso Restrito
dc.subjectQuímica
dc.subjectTripanossomo
dc.subjectProdutos de ação antimicrobiana
dc.subject.otherNaftifina
dc.subject.otherTrypanosoma cruzi
dc.subject.otherClick chemistry
dc.titleSynthesis of potential anti-trypanosoma cruzi azole-naftifine analogues by azide-alkyne click reaction
dc.typeArtigo de periódico
local.citation.epage197
local.citation.issue2
local.citation.spage195
local.citation.volume28
local.description.resumoTwenty novel azole-naftifine analogues were obtained using azide–alkyne click reaction. Five of them were more potent than the positive control naftifine revealing an unprecedented antiproliferative effects against Trypanosoma cruzi.
local.identifier.orcidhttps://orcid.org/0000-0002-1075-8830
local.identifier.orcidhttps://orcid.org/0000-0001-9004-0927
local.identifier.orcidhttps://orcid.org/0000-0003-0546-2549
local.identifier.orcidhttps://orcid.org/0000-0003-2344-5590
local.publisher.countryBrasil
local.publisher.departmentICX - DEPARTAMENTO DE QUÍMICA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S0959943618300786

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