Biomimetic nanovesicles-sources, design, production methods, and applications

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dc.creatorMarcel Franco Mougenot
dc.creatorVanessa Sousa Pereira
dc.creatorAna Letícia Rodrigues Costa Lelis
dc.creatorMarcelo Lancellotti
dc.creatorMarimelia Aparecida Porcionatto
dc.creatorJuliano Coelho da Silveira
dc.creatorLucimara Gaziola de la Torre
dc.date.accessioned2025-09-02T19:27:25Z
dc.date.accessioned2025-09-09T00:38:38Z
dc.date.available2025-09-02T19:27:25Z
dc.date.issued2022-09-22
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipFAPESP - Fundação de Amparo à Pesquisa do Estado de São Paulo
dc.format.mimetypepdf
dc.identifier.doi10.3390/pharmaceutics14102008
dc.identifier.issn19994923
dc.identifier.urihttps://hdl.handle.net/1843/84789
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.rightsAcesso Aberto
dc.subjectNanovesículas biomiméticas
dc.subject.otherLipossomo
dc.subject.otherAdministração de medicamentos
dc.subject.otherAdministração de genes
dc.subject.otherVacina
dc.subject.otherNanotecnologia
dc.subject.otherVesículas extracelulares
dc.titleBiomimetic nanovesicles-sources, design, production methods, and applications
dc.typeArtigo de periódico
local.citation.epage25
local.citation.issue10
local.citation.spage1
local.citation.volume14
local.description.resumoDespite all the progress in the field of liposomes and nanoparticles for applications as drug and gene delivery systems, the specific targeting and immune system escape capabilities of these systems are still limited. Biomimetic nanovesicles emerged as a strategy to overcome these and other limitations associated with synthetic carriers, such as short circulation time, cytotoxicity, and difficulty in crossing biological barriers, since many of the desirable abilities of drug delivery systems are innate characteristics of biological vesicles. Thus, the question arises: would biomimetic nanovesicles be responsible for addressing these advances? It is currently known that biomimetic nanovesicles (BNV) can combine the intrinsic advantages of natural materials with the well-known production methods and controllability of synthetic systems. Besides, the development of the biotechnology and nanotechnology fields has provided a better understanding of the functionalities of biological vesicles and the means for the design and production of biomimetic nanovesicles (BNV). Based on this, this work will focus on tracking the main research on biomimetic nanovesicles (BNV) applied as drug and gene delivery systems, and for vaccines applications. In addition, it will describe the different sources of natural vesicles, the technical perspectives on obtaining them, and the possibility of their hybridization with synthetic liposomes.
local.publisher.countryBrasil
local.publisher.departmentFAR - DEPARTAMENTO DE ALIMENTOS
local.publisher.initialsUFMG
local.url.externahttps://www.mdpi.com/1999-4923/14/10/2008

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