The effect of antimicrobial photodynamic therapy adjunct to non-surgical periodontal therapy on the treatment of periodontitis in individuals with type 2 diabetes mellitus: a systematic review and meta-analysis

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dc.creatorPierre Geraldo Braz da Silva-Junior
dc.creatorFernando de Oliveira Costa
dc.creatorLucas Guimarães Abreu
dc.creatorLuís Otávio de Miranda Cota
dc.creatorRafael Paschoal Esteves Lima
dc.date.accessioned2024-09-24T19:53:45Z
dc.date.accessioned2025-09-09T01:21:30Z
dc.date.available2024-09-24T19:53:45Z
dc.date.issued2023
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1016/j.pdpdt.2023.103573
dc.identifier.issn1873-1597
dc.identifier.urihttps://hdl.handle.net/1843/76855
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofPhotodiagnosis and Photodynamic Therapy
dc.rightsAcesso Restrito
dc.subjectDiabetes mellitus
dc.subjectDiabetes mellitus, type 2
dc.subjectPeriodontitis
dc.subjectPeriodontal diseases
dc.subjectPhotochemotherapy
dc.subjectHemorrhage
dc.subjectEvaluation study
dc.subjectSystematic review
dc.subjectNetwork meta-analysis
dc.subject.otherDiabetes mellitus
dc.subject.otherType 2
dc.subject.otherPeriodontitis
dc.subject.otherPeriodontal diseases
dc.subject.otherPhotodynamic therapy
dc.titleThe effect of antimicrobial photodynamic therapy adjunct to non-surgical periodontal therapy on the treatment of periodontitis in individuals with type 2 diabetes mellitus: a systematic review and meta-analysis
dc.typeArtigo de periódico
local.citation.spage103573
local.citation.volume42
local.description.resumoBackground: The purpose of the present systematic review and meta-analysis was to assess the impact of antimicrobial photodynamic therapy adjunct to non-surgical periodontal treatment on individuals with type 2 diabetes mellitus. Methods: The Preferred Reporting Items for Systematic Reviews and Meta-analyses statement was followed. Searches were carried out in six databases without restriction regarding publication year. Studies comparing periodontal clinical parameters among individuals submitted to non-surgical periodontal therapy associated with antimicrobial photodynamic therapy and a control group of individuals submitted to only non-surgical periodontal treatment were included. Study selection, data extraction, and risk of bias assessment (RoB 2.0) were performed by two review authors. Meta-analysis was performed. Mean difference (MD) and 95% confidence interval (CI) were provided. Results: Two hundred and five studies were identified and 11 studies were included. The meta-analysis demonstrated that antimicrobial photodynamic therapy adjunctive to periodontal therapy, in individuals with diabetes, resulted in a greater reduction of bleeding on probing at 6 months and in probing depth at 3 and 6 months in comparison to periodontal treatment alone (p<0.05). The included studies exhibited low risk of bias. Conclusion: Antimicrobial photodynamic therapy adjunct to periodontal therapy contributes to the improvement of periodontal clinical parameter bleeding on probing and probing depth in individuals with type 2 diabetes mellitus.
local.identifier.orcidhttps://orcid.org/0000-0002-7687-1238
local.identifier.orcidhttps://orcid.org/0000-0003-2258-8071
local.identifier.orcidhttps://orcid.org/0000-0003-1517-5842
local.identifier.orcidhttps://orcid.org/0000-0002-9140-8997
local.identifier.orcidhttps://orcid.org/0000-0003-4343-3845
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S1572100023003009?via%3Dihub

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