Cutaneous mast cell tumor in a captive Bush dog (Speothos venaticus): pathological and immunophenotypical aspects - case report
| dc.creator | Daniel Oliveira Dos Santos | |
| dc.creator | Ayisa Rodrigues Oliveira | |
| dc.creator | Thaynara Parente de Carvalho | |
| dc.creator | Nayara Ferreira De Paula | |
| dc.creator | Herlandes Penha Tinoco | |
| dc.creator | Carlyle Mendes Coelho | |
| dc.creator | Angela Pessanha Ribeiro | |
| dc.creator | Guilherme Martins | |
| dc.creator | Emerson Soares Veloso | |
| dc.creator | Enio Ferreira | |
| dc.creator | Felipe Pierezan | |
| dc.creator | Renato de Lima Santos | |
| dc.date.accessioned | 2023-07-17T20:01:10Z | |
| dc.date.accessioned | 2025-09-08T23:31:26Z | |
| dc.date.available | 2023-07-17T20:01:10Z | |
| dc.date.issued | 2021 | |
| dc.description.abstract | Um cachorro-vinagre (Speothos venaticus) apresentou um nódulo cutâneo pequeno na região perianal. Histologicamente havia neoplasia cutânea de células redondas e ulcerada, constituída por mastócitos bem diferenciados, com abundantes grânulos citoplasmáticos metacromáticos na coloração de Giemsa e infiltrado eosinofílico difuso. A imuno-histoquímica demonstrou que 30% das células neoplásicas eram positivas para a proteína Kit no citoplasma e na membrana celular. As células foram negativas para MAC e CD3. Menos de 10% das células neoplásicas foram positivas para Ki67. Durante a necropsia, foram identificados outros tumores primários, como adenoma intestinal, adenoma cortical da adrenal e tumor de células intersticiais do testículo. | |
| dc.description.sponsorship | CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico | |
| dc.description.sponsorship | FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais | |
| dc.description.sponsorship | CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior | |
| dc.format.mimetype | ||
| dc.identifier.doi | https://doi.org/10.1590/1678-4162-12251 | |
| dc.identifier.issn | 1678-4162 | |
| dc.identifier.uri | https://hdl.handle.net/1843/56480 | |
| dc.language | eng | |
| dc.publisher | Universidade Federal de Minas Gerais | |
| dc.relation.ispartof | Arquivo Brasileiro de Medicina Veterinária e Zootecnia | |
| dc.rights | Acesso Aberto | |
| dc.subject | Cães | |
| dc.subject | Imuno-histoquímica | |
| dc.subject | Tumores em animais | |
| dc.subject.other | Wild canids | |
| dc.subject.other | Immunohistochemistry | |
| dc.subject.other | Multiple tumors | |
| dc.title | Cutaneous mast cell tumor in a captive Bush dog (Speothos venaticus): pathological and immunophenotypical aspects - case report | |
| dc.title.alternative | Mastocitoma cutâneo em um cachorro-do-mato vinagre (Speothos venaticus) de cativeiro: aspectos patológicos e imunofenotípicos - relato de caso | |
| dc.type | Artigo de periódico | |
| local.citation.epage | 1104 | |
| local.citation.issue | 5 | |
| local.citation.spage | 1099 | |
| local.citation.volume | 73 | |
| local.description.resumo | A senile male captive bush dog (Speothos venaticus) presented a small perianal cutaneous nodule. Histologically, there was an ulcerated round cell tumor composed of well differentiated mast cells with abundant intracytoplasmic purple Giemsa-positive granules, with a diffuse eosinophilic infiltrate. Immunohistochemistry revealed that 30% of the neoplastic cells were positive for Kit in the cytoplasm and cell membrane, and all neoplastic cells were negative for MAC and CD3. Less than 10% of the neoplastic cells were positive for Ki67. At necropsy other primary tumors were identified in this animal, including an intestinal adenoma, an adrenal cortex adenoma and a testicular interstitial cell tumor. | |
| local.identifier.orcid | https://orcid.org/0000-0002-3083-1572 | |
| local.identifier.orcid | https://orcid.org/0000-0002-9031-792X | |
| local.identifier.orcid | https://orcid.org/0000-0002-7158-8249 | |
| local.identifier.orcid | https://orcid.org/0000-0002-2506-1163 | |
| local.identifier.orcid | https://orcid.org/0000-0003-4270-5503 | |
| local.identifier.orcid | https://orcid.org/0000-0002-5689-6198 | |
| local.identifier.orcid | https://orcid.org/0000-0003-0339-1767 | |
| local.identifier.orcid | https://orcid.org/0000-0002-4317-4233 | |
| local.identifier.orcid | https://orcid.org/0000-0003-4696-7738 | |
| local.identifier.orcid | https://orcid.org/0000-0002-1835-0303 | |
| local.identifier.orcid | https://orcid.org/0000-0002-3319-8784 | |
| local.identifier.orcid | https://orcid.org/0000-0002-4830-0470 | |
| local.publisher.country | Brasil | |
| local.publisher.department | ICB - DEPARTAMENTO DE PATOLOGIA | |
| local.publisher.department | VET - DEPARTAMENTO DE CLÍNICA E CIRURGIA | |
| local.publisher.initials | UFMG | |
| local.url.externa | https://www.scielo.br/j/abmvz/a/87YBkFBwxCGN9Ljp5TV5X7n/?lang=en |
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