Influence of biomaterials on scintigraphic diagnosis of periprosthetic infections. Ceftizoxime-99m technetium model

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dc.creatorLuiz Eduardo Moreira Teixeira
dc.creatorBruno Jannotti Pádua
dc.creatorAndré Moreira Castilho
dc.creatorIvana Duval de Araújo
dc.creatorMarco Antônio Percope de Andrade
dc.creatorValbert Nascimento Cardoso
dc.creatorSimone Odília Antunes Fernandes
dc.creatorJefferson Soares Leal
dc.creatorIsabella Kuniko Takenaka
dc.date.accessioned2022-04-07T22:57:50Z
dc.date.accessioned2025-09-08T22:59:24Z
dc.date.available2022-04-07T22:57:50Z
dc.date.issued2018-01
dc.format.mimetypepdf
dc.identifier.doi10.1590/s0102-865020180010000002
dc.identifier.issn1678-2674
dc.identifier.urihttps://hdl.handle.net/1843/40907
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofActa Cirúrgica Brasileira
dc.rightsAcesso Aberto
dc.subjectBiomateriais
dc.subjectInfecções periprotéticas
dc.subjectCeftizoxima-99m
dc.subject.otherBiocompatible materials
dc.subject.otherRadionuclide imaging
dc.subject.otherProsthesis-related infections
dc.subject.otherRats
dc.titleInfluence of biomaterials on scintigraphic diagnosis of periprosthetic infections. Ceftizoxime-99m technetium model
dc.typeArtigo de periódico
local.citation.epage21
local.citation.issue1
local.citation.spage14
local.citation.volume33
local.description.resumoPurpose: To compare the influence of two metallic implants in the diagnosis of periprosthetic infection using 99m technetium-labeled ceftizoxime. Methods: Twenty rats were randomly divided into four groups, which received sterile and contaminated titanium and stainless steel implants. After 3 weeks, scintilographic images were obtained using a gamma chamber. Radioactivity counts were obtained for the region of interest (ROI) on the operated and non-operated paws. Results: Groups A, B, and C showed homogenous distribution of the radiopharmaceutical. Hyper uptake was observed in the operated paw from group D. The ROI target count was higher in the two groups with stainless steel implants. Among the control groups, the count was higher in the stainless steel group. Furthermore, among the contaminated groups, the uptake was higher in the stainless steel group, with a significant difference. The target: non-target ratio was significantly lower in the control and contaminated groups with both titanium and stainless steel, but the comparison between control groups and contaminated groups was only significant in the former. The cpm/g observed after a decay of 48h showed statistically significant differences between groups. Conclusion: Different biomaterials used in implants have an influence on the results of scintigraphy with 99mTc-CFT.
local.publisher.countryBrasil
local.publisher.departmentFAR - DEPARTAMENTO DE ALIMENTOS
local.publisher.departmentFAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICAS
local.publisher.departmentMED - DEPARTAMENTO DE APARELHO LOCOMOTOR
local.publisher.departmentMED - DEPARTAMENTO DE CIRURGIA
local.publisher.initialsUFMG
local.url.externahttps://www.scielo.br/j/acb/a/R4FJhBs5vHXdHPLVhk3TYrf/?lang=en#

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