Omega 3 consumption and anxiety disorders: a cross-sectional analysis of the brazilian longitudinal study of adult health (elsa-brasil)

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dc.creatorLara Natacci
dc.creatorAndré r. Brunoni
dc.creatorPaulo a. Lotufo
dc.creatorIsabela m. Bensenor
dc.creatorDirce m. Marchioni
dc.creatorAlessandra c. Goulart
dc.creatorMaria Nunes
dc.creatorArlinda b. Moreno
dc.creatorLetícia o. Cardoso
dc.creatorLuana Giatti Gonçalves
dc.creatorMaria b. Molina
dc.creatorItamar s. Santos
dc.date.accessioned2023-09-28T21:15:45Z
dc.date.accessioned2025-09-08T23:31:48Z
dc.date.available2023-09-28T21:15:45Z
dc.date.issued2018-05-24
dc.format.mimetypepdf
dc.identifier.doi10.3390/nu10060663
dc.identifier.issn20726643
dc.identifier.urihttps://hdl.handle.net/1843/59010
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofNutrients
dc.rightsAcesso Aberto
dc.subjectAnxiety Disorders
dc.subjectMental Disorders
dc.subjectFatty Acids, Unsaturated
dc.subject.otherAnxiety Disorders
dc.subject.otherMental Disorders
dc.subject.otherPolyunsaturated fatty acids
dc.subject.otherω-3 fatty acids
dc.subject.otherNutrition intake
dc.titleOmega 3 consumption and anxiety disorders: a cross-sectional analysis of the brazilian longitudinal study of adult health (elsa-brasil)
dc.typeArtigo de periódico
local.citation.epage12
local.citation.issue663
local.citation.spage1
local.citation.volume10
local.description.resumoFew studies have evaluated the association between diet and mental disorders, and it has been established that ω-3 (n-3) fatty acids may have a beneficial effect for sufferers of anxiety disorders. This study is part of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)—a population-based cohort study on diet and mental health—and searched for associations between anxiety disorders and consumption of n-3 polyunsaturated fatty acids (PUFA). The study had a cross-sectional design, with a total sample of 12,268 adults. Dietary exposure was measured by a quantitative food-frequency questionnaire, and mental diagnoses were assessed by the Clinical Interview Schedule—Revised Version and diagnosed according to the International Classification of Diseases (ICD-10). Logistic regression models were built using quintiles of n-3, ω 6 (n-6), n-6/n-3 ratio, and PUFA, using the 1st quintile as reference. Anxiety disorders were identified in 15.4% of the sample. After adjusting for sociodemographic variables, cardiovascular risk factors, diet variables, and depression, intakes in the 5th quintile were inversely associated with anxiety disorders for EPA (OR = 0.82, 95% CI = 0.69–0.98), DHA (OR = 0.83, 95% CI = 0.69–0.98), and DPA (OR = 0.82, 95% CI = 0.69–0.98). Participants in the fifth quintile of n-6/n-3 ratio had a positive association with anxiety disorders. Although results suggest a possible protective effect of n-3 fatty acids against anxiety, all associations lost significance after adjustment for multiple comparison
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE MEDICINA PREVENTIVA SOCIAL
local.publisher.initialsUFMG
local.url.externahttps://www.mdpi.com/2072-6643/10/6/663

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