Ação in vitro de agentes de limpeza e da ceftarolina em patógenos associados à dermatopatias em cães

Abstract

Bacterial resistance to antimicrobials is a multifactorial problem with microbiological, therapeutic, epidemiological and public health implications. The indiscriminate use of antimicrobials has contributed substantially to the increase of resistance. The use of antiseptics has gained importance in veterinary medicine, since there is no evidence of resistance to these products. This approach would lead to lower favoring of resistance selection of the commensal microbiota. Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a constant medical concern. Ceftaroline-fosamyl, -lactam with anti-MRSA action, has recently been approved for use in humans with rare resistance descriptions. Reports of resistance to ceftarolin by Staphylococcus pseudintermedius, the main bacterium that causes dermatopathies in dogs, are non-existent. The objective of this work was to evaluate the in vitro action of atrial cleansing products on microorganisms associated with otitis in dogs and to evaluate the resistance to ceftaroline by methicillin resistant Staphylococcus pseudintermedius (MRSP). Ear cleanears with lactic acid showed antimicrobial activity, as well as salicylic acid and boric acid products showed good diffusion capacity in vitro. The resistance to ceftaroline by MRSP found in this study was higher than those described in MRSA.