Implications of preoperative arterial stiffness for patients treated with endovascular repair of abdominal aortic aneurysms

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dc.creatorCarly Thaxton
dc.creatorMasaki Kano
dc.creatorDaniel Mendes Pinto
dc.creatorTúlio Pinho Navarro
dc.creatorToshiya Nishibe
dc.creatorAlan Dardik
dc.date.accessioned2026-01-09T20:55:16Z
dc.date.issued2024-05-09
dc.identifier.doihttps://doi.org/10.1016/j.jvssci.2024.100209
dc.identifier.issn2666-3503
dc.identifier.urihttps://hdl.handle.net/1843/1358
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJVS-Vascular Science
dc.rightsAcesso aberto
dc.rightsCC0 1.0 Universalen
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/
dc.subjectAneurisma da aorta abdominal
dc.subjectCirurgia vascular
dc.subjectReparo endovascular de aneurisma
dc.subjectExame vascular
dc.subjectSaco aneurismático
dc.subject.otherVascular stiffness
dc.subject.otherPulse wave analysis
dc.subject.otherEndovascular aneurysm repair
dc.subject.otherAortic aneurysm
dc.subject.otherAbdominal
dc.titleImplications of preoperative arterial stiffness for patients treated with endovascular repair of abdominal aortic aneurysms
dc.typeArtigo de periódico
local.citation.epage13
local.citation.spage1
local.citation.volume5
local.description.resumoArterial stiffening is associated with adverse cardiovascular patient outcomes; stiffness may also be associated with postsurgical events and has been suggested to be a fundamental mechanism in the pathogenesis of aortic aneurysms. Although open repair of aneurysms decreases aortic stiffness, implantation of a rigid endograft is associated with increased aortic stiffness after endovascular aneurysm repair (EVAR). This review provides an overview of aortic wall physiology and the contemporary understanding of aortic stiffness and its implications for patients undergoing abdominal aortic aneurysm repair. Recent data suggests that increased central arterial stiffness, estimated preoperatively using the pulse wave velocity (PWV), may predict aneurysm sac behavior after EVAR, with elevated preoperative PWV associated with less sac shrinkage, and even sac enlargement, after EVAR. With the development of several simple noninvasive methods to measure PWV, such as brachial-ankle PWV and single cuff brachial oscillometry, there may be a role for monitoring ambulatory PWV to predict outcomes after EVAR. Additionally, because aortic stiffness is associated with adverse cardiovascular outcomes, and EVAR increases aortic stiffness, assessment of aortic stiffness before aortic interventions may help to guide therapeutic decisions as well as surveillance protocols, leading to optimized patient outcomes.
local.publisher.countryBrasil
local.publisher.departmentMEDICINA - FACULDADE DE MEDICINA
local.publisher.initialsUFMG
local.subject.cnpqCIENCIAS DA SAUDE
local.url.externahttps://www.sciencedirect.com/science/article/pii/S2666350324000208?ref=pdf_download&fr=RR-2&rr=9bb5785e5de0f17d

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