Hospital-acquired intestinal toxemia botulism in a newly diagnosed adult colon cancer patient

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dc.creatorLucas José Sá da Fonseca
dc.creatorDiogo Couto de Carvalho
dc.creatorHelena Providelli de Moraes
dc.creatorIzabela Dayany França Feitosa
dc.creatorGil Pereira Neto
dc.creatorRodrigo Vasconcellos Vilela
dc.creatorBreno Franco Silveira Fernandes
dc.creatorRodrigo Santiago Gomez
dc.creatorVandack Nobre
dc.date.accessioned2024-11-05T22:41:02Z
dc.date.accessioned2025-09-09T00:30:45Z
dc.date.available2024-11-05T22:41:02Z
dc.date.issued2019
dc.format.mimetypepdf
dc.identifier.doi10.1590/s1678-9946201961049
dc.identifier.issn1678-9946
dc.identifier.urihttps://hdl.handle.net/1843/77840
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofRevista do Instituto de Medicina Tropical de São Paulo
dc.rightsAcesso Aberto
dc.subjectBotulismo
dc.subjectNeuropatia
dc.subjectDiagnóstico
dc.subjectJunção Neuromuscular
dc.subjectClostridium botulinum
dc.titleHospital-acquired intestinal toxemia botulism in a newly diagnosed adult colon cancer patient
dc.typeArtigo de periódico
local.citation.epage4
local.citation.spage1
local.citation.volume61
local.description.resumoThis manuscript reports a case of intestinal toxemia botulism in an adult with recently diagnosed metastatic colon cancer in whom botulism symptoms began 23 days after hospital admission. Representing the rarest form of botulism presentation in clinical practice, this infectious disease may have developed due to a cluster of predisposing factors that favored Clostridium botulinum colonization and the endogenous production of neurotoxins, among which are previous use of broad-spectrum antibiotics and colon changes related to the development of the neoplasia. This case highlights the importance of considering intestinal toxemia botulism in the differential diagnosis of a patient presenting with symmetrical descending flaccid paralysis, since immediate treatment with botulinum antitoxin may improve clinical outcomes.
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICA
local.publisher.initialsUFMG
local.url.externahttps://www.scielo.br/j/rimtsp/a/BcjpzVnHy3C3ZbvTBsqW5Pb/

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