Prevalence of vitamin d deficiency and its relationship with factors associated with recurrent wheezing

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Artigo de periódico

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Membros da banca

Resumo

Objective: To determine the prevalence of vitamin D defi ciency/insuffi ciency in children 0-18 years of age with recurrent wheezing and/or asthma residing in the microregion of Viçosa, Minas Gerais, Brazil, and treated at a referral center, and to determine its association with major risk factors for wheezing. Methods: A cross-sectional study was performed using a semi-structured questionnaire, which was administered by trained interviewers to the legal guardians of the study participants. Data were obtained regarding general characteristics of recurrent wheezing; general sociodemographic, environmental, and biologic factors; and atopy-related factors. The magnitude of the statistical association was assessed by calculating ORs and their corresponding 95% CIs by using multiple logistic regression. Results: We included 124 children in the study. The prevalence of vitamin D defi ciency/insuffi ciency in the sample was 57.3%. Vitamin D deficiency/insufficiency was found to be associated with wheezing in the fi rst year of life, personal history of atopic dermatitis, environmental pollution, and vitamin D supplementation until 2 years of age. Conclusions: The prevalence of vitamin D defi ciency/insuffi ciency was high in our sample. Vitamin D concentrations were directly associated with vitamin D supplementation until 2 years of age and were inversely associated with wheezing events in the fi rst year of life, personal history of atopic dermatitis, and environmental pollution.

Abstract

Assunto

Asthma, Vitamin D, Respiratory Sounds

Palavras-chave

Asthma, Sibilância, Vitamina D

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Curso

Endereço externo

https://doi.org/10.1590/1806-3713/e20170431

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