Determinants of quality of life in Brazilian patients with myasthenia gravis

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dc.creatorAline Mansueto Mourão
dc.creatorRodrigo Santiago Gomez
dc.creatorLuiz Sergio Mageste Barbosa
dc.creatorDenise da Silva Freitas
dc.creatorElizabeth Regina Comini Frota
dc.creatorArthur Melo e Kummer
dc.creatorStela Maris Aguiar Lemos
dc.creatorAntônio Lucio Teixeira
dc.date.accessioned2024-11-04T20:29:21Z
dc.date.accessioned2025-09-08T23:01:05Z
dc.date.available2024-11-04T20:29:21Z
dc.date.issued2016-07
dc.format.mimetypepdf
dc.identifier.issn2289-2920
dc.identifier.urihttps://hdl.handle.net/1843/77803
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofClinics
dc.rightsAcesso Aberto
dc.subjectMiastenia Gravis
dc.subjectQualidade de Vida
dc.subjectPsicometria
dc.subjectNeuropsiquiatria
dc.titleDeterminants of quality of life in Brazilian patients with myasthenia gravis
dc.typeArtigo de periódico
local.citation.epage374
local.citation.issue7
local.citation.spage370
local.citation.volume71
local.description.resumoOBJECTIVES: The aims of the current study were 1) to evaluate the reliability and validity of the Brazilian version of the 15-item Myasthenia Gravis Quality of Life Scale and 2) to investigate the quality of life of Brazilian patients with myasthenia gravis and its determinants. METHODS: This cross-sectional study included 69 patients with myasthenia gravis who underwent neurological evaluation and completed questionnaires regarding quality of life (the 36-item Short Form of the Medical Outcomes Study and the 15-item Myasthenia Gravis Quality of Life Scale), anxiety and depressive symptoms. RESULTS: The Brazilian version of the 15-item Myasthenia Gravis Quality of Life Scale showed high internal consistency and good concurrent validity with the 36-item Short Form of the Medical Outcomes Study and its subscales. Determinants of quality of life in Brazilian patients with myasthenia gravis included the current status of myasthenia gravis as assessed by the Myasthenia Gravis Composite, the current prednisone dose and the levels of anxiety and depression. CONCLUSION: The Brazilian version of the 15-item Myasthenia Gravis Quality of Life Scale is a valid instrument. Symptom severity, prednisone dosage and anxiety and depression levels impact the quality of life of patients with myasthenia gravis.
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE SAÚDE MENTAL
local.publisher.initialsUFMG
local.url.externahttps://www.scielo.br/j/clin/a/YRMLsqgSQR7pxf3Bt5YmshC/abstract/?lang=en#

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