Low back pain, obesity, and inflammatory markers: exercise as potential treatment

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dc.creatorIsabela Maia de Cruz Fernandes
dc.creatorRafael Zambelli de Almeida Pinto
dc.creatorPaulo Ferreira
dc.creatorFábio Santos de Lira
dc.date.accessioned2023-01-16T13:35:55Z
dc.date.accessioned2025-09-08T23:19:31Z
dc.date.available2023-01-16T13:35:55Z
dc.date.issued2018
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.description.sponsorshipFAPESP - Fundação de Amparo à Pesquisa do Estado de São Paulo
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.12965/jer.1836070.035
dc.identifier.issn2288-1778
dc.identifier.urihttps://hdl.handle.net/1843/48939
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJournal of Exercise Rehabilitation
dc.rightsAcesso Aberto
dc.subjectDor lombar
dc.subjectObesidade
dc.subjectComportamento sedentário
dc.subjectProteína C-reativa
dc.subjectProstaglandinas
dc.subject.otherLow back pain
dc.subject.otherObesity
dc.subject.otherSedentary lifestyle
dc.subject.otherC-reactive protein
dc.subject.otherProstaglandins
dc.titleLow back pain, obesity, and inflammatory markers: exercise as potential treatment
dc.typeArtigo de periódico
local.citation.epage174
local.citation.issue2
local.citation.spage168
local.citation.volume14
local.description.resumoLow back pain is a health issue with significant impact to patients and society. This narrative review aims to synthesize the relationship between obesity, low-grade inflammation and low back pain. It is known that a sedentary lifestyle is a risk factor for obesity and related disorders. The adipose tissue of obese people secretes a range of cytokines of character pro- and anti-inflammatory, with many molecular effects. In addition, pro-inflammatory cytokines are sensitizers of C-reactive protein (CRP), a marker of acute inflammation that can be linked to the musculoskeletal pain sensation individuals with back pain. Another inflammatory marker deserves mention, prostaglandin E2. Prostaglandin E2 is important in the process of triggering actions such as pyrexia, sensation of pain and inflammation, which are exhibited in low back pain condition. The potential for exercises and physical activity to control these mediators and act as a preventative measure for back pain are important because they work as a nonpharmacological strategy to this target audience. There are two types of exercise discussed in this review, the moderate-intensity continuous training and high-intensity interval training.
local.identifier.orcidhttps://orcid.org/0000-0003-3347-7203
local.identifier.orcidhttps://orcid.org/0000-0002-2775-860X
local.identifier.orcidhttps://orcid.org/0000-0002-5861-7770
local.identifier.orcidhttps://orcid.org/0000-0002-9645-1003
local.publisher.countryBrasil
local.publisher.departmentEEF - DEPARTAMENTO DE FISIOTERAPIA
local.publisher.initialsUFMG
local.url.externahttps://www.e-jer.org/journal/view.php?year=2018&vol=14&page=168

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