Sharp DNA denaturation in a helicoidal mesoscopic model

Página do item simplificado
dc.creatorMateus Rodrigues Leal
dc.creatorGerald Weber
dc.date.accessioned2024-03-11T15:23:10Z
dc.date.accessioned2025-09-08T22:57:22Z
dc.date.available2024-03-11T15:23:10Z
dc.date.issued2020
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1016/j.cplett.2020.137781
dc.identifier.issn0009-2614
dc.identifier.urihttps://hdl.handle.net/1843/65652
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofChemical Physics Letters
dc.rightsAcesso Aberto
dc.subjectDNA
dc.subject.otherDNA stability
dc.subject.otherMesoscopic models
dc.subject.otherPeyrard Bishop model
dc.titleSharp DNA denaturation in a helicoidal mesoscopic model
dc.typeArtigo de periódico
local.citation.epage7
local.citation.spage1
local.citation.volume755
local.description.resumoThe Peyrard-Bishop DNA model describes the molecular interactions with simple potentials which allow efficient calculations of melting temperatures. However, it is based on a Hamiltonian that does not consider the helical twist or any other relevant molecular dimensions. Here, we start from a more realistic 3D model and work out several approximations to arrive at a new non-linear 1D Hamiltonian with a twist angle dependence. Our approximations were numerically compared to full 3D calculations, and established its validity in the regime of small angles. For long DNA sequences we obtain sharp, first-order-like melting, transitions.
local.identifier.orcidhttps://orcid.org/0000-0001-8233-356X
local.identifier.orcidhttps://orcid.org/0000-0002-2935-1571
local.publisher.countryBrasil
local.publisher.departmentICX - DEPARTAMENTO DE FÍSICA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S0009261420306965?via%3Dihub

Arquivos

Pacote original

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
Sharp DNA denaturation in a helicoidal mesoscopic model.pdf
Tamanho:
1.26 MB
Formato:
Adobe Portable Document Format
Baixar

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG