Erythema multiforme induced by alendronate sodium in a geriatric patient: a case report and review of the literature

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dc.creatorJosé-Alcides Almeida de Arruda
dc.creatorPedro Silva
dc.creatorMárcio-Bruno Amaral
dc.creatorFernanda Cotta
dc.creatorRenata Avendanho
dc.creatorRicardo Alves de Mesquita
dc.date.accessioned2024-10-14T12:21:32Z
dc.date.accessioned2025-09-09T01:33:42Z
dc.date.available2024-10-14T12:21:32Z
dc.date.issued2017-07-01
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.4317%2Fjced.53653
dc.identifier.issn1989-5488
dc.identifier.urihttps://hdl.handle.net/1843/77408
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJournal of Clinical and Experimental Dentistry
dc.rightsAcesso Aberto
dc.subjectErythema multiforme
dc.subjectTherapeutics
dc.subjectDiagnosis
dc.subjectAlendronate
dc.subjectLip
dc.subjectUlcer
dc.subject.otherAdverse events
dc.subject.otherErythema multiforme
dc.subject.otherTherapeutics
dc.subject.otherDiagnosis
dc.subject.otherAlendronate
dc.titleErythema multiforme induced by alendronate sodium in a geriatric patient: a case report and review of the literature
dc.typeArtigo de periódico
local.citation.epage933
local.citation.issue7
local.citation.spage929
local.citation.volume9
local.description.resumoErythema multiforme is an uncommon acute inflammatory disorder caused by exposure to microbes or drugs. Erythema multiforme minor typically affects only one mucosa and can be associated with symmetrical target skin lesions on the extremities. The disease usually occurs in patients in their 3rd and 4th decade of life, but can also affect children and adolescents. Alendronate sodium has been approved for the prevention and treatment of osteoporosis in postmenopausal women, but is associated with adverse events. This study reports and discusses a case of erythema multiforme minor. In addition, a literature search of articles published in PubMed-Medline was performed. The case was a 96-year-old woman who had taken alendronate. Intraoral clinical examination demonstrated hypersalivation and macrocheilia of the lower lip, associated with an ill-defined ulcer with erythematous borders measuring 20 mm in greatest diameter and covered with serofibrinous exudates. The aging of the population in developed and developing countries has increased the use of alendronate sodium to prevent osteoporosis and clinicians should be aware of possible oral adverse events associated with this drug.
local.identifier.orcidhttps://orcid.org/0000-0002-6599-3950
local.identifier.orcidhttps://orcid.org/0000-0003-3207-4007
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549594/

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