Challenges for the Implementation of the First Large-Scale Rheumatic Heart Disease Screening Program in Brazil: The PROVAR Study Experience

Página do item simplificado
dc.creatorJulia Pereira Afonso Dos Santos
dc.creatorGabriel Assis Lopes do Carmo
dc.creatorAndrea Zawacki Beaton
dc.creatorTainá Vitti Lourenço
dc.creatorAdriana Costa Diamantino
dc.creatorMaria do Carmo Pereira Nunes
dc.creatorCraig Sable
dc.creatorBruno Ramos Nascimento
dc.date.accessioned2023-08-14T22:28:21Z
dc.date.accessioned2025-09-09T00:17:31Z
dc.date.available2023-08-14T22:28:21Z
dc.date.issued2017
dc.format.mimetypepdf
dc.identifier.doi10.5935/abc.20170047
dc.identifier.issn0066782X
dc.identifier.urihttps://hdl.handle.net/1843/57822
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofArquivos Brasileiros de Cardiologia
dc.rightsAcesso Aberto
dc.subjectCardiopatia Reumática
dc.subjectProgramas de Rastreamento
dc.subjectEchocardiography
dc.subjectSaúde da criança
dc.subjectSaúde do Adolescente
dc.subject.otherRheumatic Heart Disease
dc.subject.otherMass Screening
dc.subject.otherEchocardiography
dc.subject.otherChild Health
dc.subject.otherAdolescent Health
dc.titleChallenges for the Implementation of the First Large-Scale Rheumatic Heart Disease Screening Program in Brazil: The PROVAR Study Experience
dc.typeArtigo de periódico
local.citation.epage374
local.citation.issue4
local.citation.spage370
local.citation.volume108
local.description.resumoRheumatic Heart Disease (RHD) is the cardiac consequence of acute rheumatic fever (ARF), an inflammatory disease triggered by streptococcal pharyngitis. Although the prevalence of RHD has decreased in high-income countries, lack of social and economic development and poor primary prevention – mainly in in low- and middle-income countries – perpetuate an environment where RHD remains endemic. It is estimated that RHD continues to affect nearly 33 million people worldwide.1 According to the World Health Organization (WHO), RHD is responsible for 1-1.5% of all cardiovascular deaths and 3-4% of cardiovascular Disability-Adjusted Life Years (DALYs).2 In Brazil, according to the Unified Health System (SUS), there were 26,054 hospital admissions for ARF (45% with cardiac compromise) between 2008 and 2015, and the total cost to SUS was US$3.5 million, a number that is most likely underestimated.3 The main burden of RHD to public health systems consists of repeated hospital admissions and cardiac surgeries in the following decades after initial cardiac damage. If RHD is detected in its early stages, secondary prophylaxis (regular penicillin injections) can be initiated to prevent new episodes of ARF, avoiding further valve damage and progression of RHD. In high prevalence regions, RHD meets the traditional screening criteria defined by Wilson and Jungner,4 although the long-term clinical significance of latent RHD is not entirely clear. Previous studies have demonstrated, however, that in 38 to 68% of asymptomatic RHD patients, echocardiographic findings show that abnormalities persist, and progress in 4 to 16%,5 reinforcing the importance of early diagnosis in susceptible populations.The PROVAR study (Programa de Rastreamento da Valvopatia Reumática – Rheumatic Heart Disease Screening Program) is the first large-scale echocardiographic screening program in Brazil, using echocardiography to estimate the prevalence of latent RHD in asymptomatic children between 5 and 18 years old attending public schools of underserved areas of the cities Belo Horizonte, Montes Claros and Bocaiúva, in the Brazilian State of Minas Gerais. Minas Gerais is the second most populous Brazilian state (>20 million inhabitants) and has a large territory, great geographical diversity and is marked by economic discrepancies between its different regions. This project is a clinical and research collaboration between the University Hospital of Universidade Federal de Minas Gerais (UFMG), Brazil, and the Children’s National Health System (CNHS) in Washington DC, United States of America (USA).
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICA
local.publisher.initialsUFMG
local.url.externahttps://www.scielo.br/j/abc/a/yzqNHCsknnhVT4wjjsKMKsv/?lang=en

Arquivos

Pacote original

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
Challenges for the Implementation of the First Large-Scale Rheumatic Heart Disease Screening Program in Brazil pdfa.pdf
Tamanho:
197.45 KB
Formato:
Adobe Portable Document Format
Baixar

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG