Oral surgery in patients under antithrombotic therapy

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dc.creatorAmanda Leal Rocha
dc.creatorAlessandra Figueiredo Souza
dc.creatorMaria Auxiliadora Parreiras Martins
dc.creatorMarina Guimarães Fraga
dc.creatorDenise Vieira Travassos
dc.creatorAna Cristina Borges-Oliveira
dc.creatorDaniel Dias Ribeiro
dc.creatorTarcília Aparecida da Silva
dc.date.accessioned2025-04-01T20:50:13Z
dc.date.accessioned2025-09-08T23:29:52Z
dc.date.available2025-04-01T20:50:13Z
dc.date.issued2018-01
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1097/mbc.0000000000000677
dc.identifier.issn1473-5733
dc.identifier.urihttps://hdl.handle.net/1843/81203
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofBlood coagulation & fibrinolysis
dc.rightsAcesso Restrito
dc.subjectHemorrhage
dc.subjectAnticoagulants
dc.subjectFibrinolytic agents
dc.subjectTooth extraction
dc.subjectWarfarin
dc.subjectRisk
dc.subjectMedical records
dc.subjectAssociation
dc.subject.otherAnticoagulants
dc.subject.otherAntithrombotic agents
dc.subject.otherHemorrhage
dc.subject.otherTooth extraction
dc.subject.otherWarfarin
dc.titleOral surgery in patients under antithrombotic therapy
dc.typeArtigo de periódico
local.citation.epage103
local.citation.issue1
local.citation.spage97
local.citation.volume29
local.description.resumoTo investigate perioperative and postoperative bleeding, complications in patients under therapy with anticoagulant or antiplatelet drugs submitted to oral surgery. To evaluate the risk of bleeding and safety for dental surgery, a retrospective chart review was performed. Medical and dental records of patients taking oral antithrombotic drugs undergoing dental surgery between 2010 and 2015 were reviewed. Results were statistically analyzed using Fisher's exact test, t test or the χ test. One hundred and seventy-nine patients underwent 293 surgical procedures. A total of eight cases of perioperative and 12 episodes of postoperative bleeding were documented. The complications were generally managed with local measures and did not require hospitalization. We found significant association of postoperative hemorrhage with increased perioperative bleeding (P = 0.043) and combination of anticoagulant and antiplatelet therapy (P < 0.001). The chance of postoperative hemorrhage for procedures with increased perioperative bleeding is 8.8 times bigger than procedures without perioperative bleeding. Dental surgery in patients under antithrombotic therapy might be carried out without altering the regimen because of low risk of perioperative and postoperative bleeding. However, patients with increased perioperative bleeding should be closely followed up because of postoperative complications risk.
local.identifier.orcidhttps://orcid.org/0000-0001-9623-7835
local.identifier.orcidhttps://orcid.org/0000-0003-2084-9557
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://journals.lww.com/bloodcoagulation/fulltext/2018/01000/oral_surgery_in_patients_under_antithrombotic.15.aspx

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