Diabetes Insípido Central associado à Carcinoma Hipofisiário: relato de caso

Abstract

This paper report a case of a central diabetes insipidus in a dog, boxer, male, ten years old, with a history of polyuria and polydipsia. During the clinical examination no abnormality was found. Complentary exams were performed, resulting in urine specific gravity lower than the physiologic parameter (1.000). The dog was incapable to increase the urine specific gravity during the 12 hours period of water privation test, and during this time developed 5% of dehydration. Eventually was administrated dDAVP (desmopressin acetate) and 4 hours after the administration the specific gravity increased to the normal value (1.035). The patient was treated with dDAVP improving the clinical signs. Afterwards, was performed a routine leishmaniosis sorology in which the dog was positive, resulting in its euthanasia. The histologic examination suggested pituitary adenocarcinoma as the central diabetes insipidus origin