Perspectives of biological analysis in latin america using multi and comprehensive two-dimensional gas chromatography: a mini-review

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dc.creatorMiriany Avelino Moreira Fernandez
dc.creatorLeiliane Coelho André
dc.creatorZenilda de Lourdes Cardeal
dc.date.accessioned2023-01-10T19:17:29Z
dc.date.accessioned2025-09-08T23:27:23Z
dc.date.available2023-01-10T19:17:29Z
dc.date.issued2020
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais
dc.description.sponsorshipOutra Agência
dc.identifier.doihttps://doi.org/10.1007/s10337-020-03910-2
dc.identifier.issn1612-1112
dc.identifier.urihttps://hdl.handle.net/1843/48836
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofChromatographia
dc.rightsAcesso Restrito
dc.subjectQuímica analítica
dc.subjectCromatografia de gás
dc.subjectAnálise cromatográfica
dc.subjectPreparação de amostra (Química)
dc.subjectPesquisa Química
dc.subjectAmérica Latina
dc.subject.otherComprehensive two-dimensional gas chromatography
dc.subject.otherMultidimensional gas chromatography
dc.subject.otherBiological samples
dc.subject.otherLatin America
dc.titlePerspectives of biological analysis in latin america using multi and comprehensive two-dimensional gas chromatography: a mini-review
dc.typeArtigo de periódico
local.citation.epage1053
local.citation.issue9
local.citation.spage1045
local.citation.volume83
local.description.resumoMulti and comprehensive two-dimensional gas chromatography application have been increasingly mentioned in different countries. This technique increases the efficiency of peak separation in chromatographic analysis, minimizing problems due to the presence of interfering compounds in the analysis, especially in complex matrices. In Latin America, it has been applied to different areas of study. However, biological samples have been reported in a small number of applications. This mini-review addresses studies where the multi and comprehensive two-dimensional gas chromatography technique have been applied to biological samples’ analyses. Biological matrices are generally complex, and sample preparation usually requires a large number of steps to minimize potential interferences. The main areas of study described were related to doping control analysis and biomarker analysis. The urine sample was the main type of biological sample used in the studies. Studies have shown that results obtained by two-dimensional gas chromatography or supported or not by mathematical tools allow high efficiency in solving problems such as coelution. However, the small number of works published with the participation of Latin American researchers indicate that equipment price, especially when mass spectrometry is used as a detector, has a limiting factor in its wide application.
local.identifier.orcidhttps://orcid.org/0000-0002-9416-9637
local.identifier.orcidhttps://orcid.org/0000-0003-1383-6299
local.publisher.countryBrasil
local.publisher.departmentFAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICAS
local.publisher.departmentICX - DEPARTAMENTO DE QUÍMICA
local.publisher.initialsUFMG
local.url.externahttps://link.springer.com/article/10.1007/s10337-020-03910-2

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