Catatonia and brain tumor: review and illustrative case report

dc.creatorThales Pimenta de Figueiredo
dc.creatorPaulo Henrique Teixeira do Prado
dc.creatorJadison Luiz Barbosa Junior
dc.creatorCaio Hage Chahine Kubrusly
dc.creatorIzabela Maria Seabra Leite
dc.creatorLuiz Filipe Silva Cororino Couto
dc.creatorPaulo Marcos Brasil Rocha
dc.date.accessioned2024-09-25T21:16:53Z
dc.date.accessioned2025-09-08T22:58:35Z
dc.date.available2024-09-25T21:16:53Z
dc.date.issued2023
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.30654/MJPMH.10041
dc.identifier.issn2474-7564
dc.identifier.urihttps://hdl.handle.net/1843/76885
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofMathews Journal of Psychiatry & Mental Health
dc.rightsAcesso Aberto
dc.subjectNeoplasias encefálicas
dc.subjectNeoplasias da mama
dc.subjectCatatonia
dc.subject.otherBrain tumor
dc.subject.otherBrain metastasis
dc.subject.otherBreast cancer
dc.subject.otherCatatonia
dc.subject.otherCatatonic syndrome
dc.titleCatatonia and brain tumor: review and illustrative case report
dc.typeArtigo de periódico
local.citation.issue3
local.citation.volume8
local.description.resumoCase Report: This literature review is accompanied by an illustrative case of a woman diagnosed with a Stage IV invasive ductal breast carcinoma who evolved with a catatonic syndrome due to a metastatic brain tumor. Objective: It aims to forward the understanding of how catatonia emerges from organic brain tumoral lesions and how can it be treated properly. Methods: After reporting the above-mentioned case, we revised the scientific literature, searching for case reports and series of cases of patients with catatonic syndrome and brain tumors. We included articles in which patients were diagnosed with one or more tumoral brain lesions. Articles in which patients with paraneoplastic syndrome, anti-NMDA encephalitis, or other encephalitis and tumor in other regions (e.g., adrenal) were reported were excluded. When feasible, all PRISMA recommendations for systematic reviews were followed. Results: As result, we have found that although catatonic syndrome is a classical diagnostic construct in psychiatry, its pathophysiology can be very diverse even when caused by a brain tumor, as no single brain region can be associated with the syndrome. Moreover, patients do appear to respond very differently to treatments implemented. However, even though not always effective, treatment with benzodiazepines (e.g., lorazepam or diazepam) can be performed since it has been successfully used in various cases of secondary catatonia due to brain tumors, including ours. Conclusion: As far as we know, this is the first case report of a brain metastatic tumor, clinically evidenced by brain imaging, secondary to breast cancer that evolved with a catatonic syndrome ever published. The significant response to the use of benzodiazepines associated with other measures suggests some reliability of interventions such as these in patients with catatonic syndrome secondary to tumoral brain lesions.
local.identifier.orcidhttps://orcid.org/0000-0003-0944-5447
local.identifier.orcidhttps://orcid.org/0000-0002-0337-1371
local.identifier.orcidhttps://orcid.org/0000-0002-0600-9052
local.identifier.orcidhttps://orcid.org/0000-0003-2314-8588
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE SAÚDE MENTAL
local.publisher.initialsUFMG
local.url.externahttps://www.mathewsopenaccess.com/journals/psychiatry-mental-health/abstract/catatonia-and-brain-tumor-review-and-illustrative-case-report

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