Association of preterm birth with poor metabolic outcomes in schoolchildren

dc.creatorCristiane Valéria Batista Pereiraabdo
dc.creatorCamila Gonçalves Miranda Shimoya Belém
dc.creatorEnrico Antonio Colosimo
dc.creatorMaria Cândida Ferrarez Bouzada Viana
dc.creatorIvani Novato Silva
dc.date.accessioned2025-08-07T19:59:04Z
dc.date.accessioned2025-09-09T00:37:59Z
dc.date.available2025-08-07T19:59:04Z
dc.date.issued2023
dc.format.mimetypepdf
dc.identifier.doi10.1016/j.jped.2023.03.001
dc.identifier.issn00217557
dc.identifier.urihttps://hdl.handle.net/1843/84187
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.rightsAcesso Aberto
dc.subjectInfant, Premature
dc.subjectMetabolic Syndrome
dc.subjectObesity
dc.subjectChildren
dc.subject.otherInfant preterm
dc.subject.otherMetabolic syndrome
dc.subject.otherObesity
dc.subject.otherChildren
dc.titleAssociation of preterm birth with poor metabolic outcomes in schoolchildren
dc.typeArtigo de periódico
local.citation.epage470
local.citation.issue5
local.citation.spage464
local.citation.volume99
local.description.resumoObjective: To investigate, at school age, the metabolic profile of children born preterm Methods: A cross-sectional study of children 5 to 8 years old, born with gestational age (GA) < 34 weeks and/or weight ≤ 1,500 grams. Clinical and anthropometric data were assessed by a single trained pediatrician. Biochemical measurements were done at the organization’s Central Laboratory using standard methods. Data on health conditions, eating, and daily life habits were retrieved from medical charts and through validated questionnaires. Binary logistic and linear regression models were built to identify the association between variables, weight excess, and GA. Results: Out of 60 children (53.3% female), 6.8 ± 0.7 years old, 16.6% presented excess weight, 13.3% showed increased insulin resistance markers and 36.7% had abnormal blood pressure values. Those presenting excess weight had higher waist circumferences and higher HOMA-IR than normal-weight children (OR = 1.64; CI = 1.035–2.949). Eating and daily life habits were not different among overweight and normal-weight children. The small-for-gestational-age (SGA) and appropriate-for-gestational-age (AGA, 83.3%) birth weight children did not differ regarding clinical (body weight, blood pressure) or biochemical variables (serum lipids, blood glucose, HOMA-IR).Conclusion: Schoolchildren born preterm, regardless of being AGA or SGA, were overweight, and presented increased abdominal adiposity, reduced insulin sensitivity, and altered lipid profile, justifying longitudinal follow-up regarding adverse metabolic outcomes in the future.
local.publisher.countryBrasil
local.publisher.departmentICX - DEPARTAMENTO DE ESTATÍSTICA
local.publisher.departmentMED - DEPARTAMENTO DE PEDIATRIA
local.publisher.initialsUFMG
local.url.externahttps://doi.org/10.1016/j.jped.2023.03.001

Arquivos

Pacote original

Agora exibindo 1 - 1 de 1
Carregando...
Imagem de Miniatura
Nome:
Growth phenotypes pdfa.pdf
Tamanho:
202.35 KB
Formato:
Adobe Portable Document Format

Licença do pacote

Agora exibindo 1 - 1 de 1
Carregando...
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição: