Factors associated with the development of leprosy in brazilian contacts: a systematic review

Página do item simplificado
dc.creatorEdilamar Silva de Alecrin
dc.creatorAna Laura Grossi de Oliveira
dc.creatorNathalia Sernizon-guimarães
dc.creatorSandra Lyon
dc.creatorMaria Auxiliadora Parreiras
dc.creatorManoel Otávio da Costa Rocha
dc.date.accessioned2024-01-11T19:29:42Z
dc.date.accessioned2025-09-08T23:56:13Z
dc.date.available2024-01-11T19:29:42Z
dc.date.issued2022
dc.format.mimetypepdf
dc.identifier.doi10.48331/scielodata.34HR6I
dc.identifier.issn16789946
dc.identifier.urihttps://hdl.handle.net/1843/62645
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofRevista do Instituto de Medicina Tropical de São Paulo
dc.rightsAcesso Aberto
dc.subjectLeprosy
dc.subjectRisk factors
dc.subjectProtective Factors
dc.subjectPublic Health Surveillance
dc.subjectSystematic Review
dc.subject.otherLeprosy
dc.subject.otherRisk factors
dc.subject.otherProtective Factors
dc.subject.otherPublic Health Surveillance
dc.subject.otherSystematic Review
dc.titleFactors associated with the development of leprosy in brazilian contacts: a systematic review
dc.typeArtigo de periódico
local.citation.epage13
local.citation.issuee55
local.citation.spage1
local.citation.volume64
local.description.resumoPeople who interact with leprosy patients in their environment, neighborhood, family, or social relationships are at risk to develop the disease. This systematic review investigated the risk and protective factors associated with the development of leprosy in Brazilian contacts. The studies were found in Cochrane Library, PubMed (MEDLINE), Embase, Virtual Health Library, grey literature and hand search until July 2021. The study selection, data extraction and quality assessment were independently performed by two investigators. The quality assessment was performed using the Newcastle-Ottawa Scale (NOS). This review was registered in PROSPERO (CRD42020160680). Seventeen articles fulfilled the inclusion criteria (n=544). The immunological and molecular factors, such as Anti-phenolic Glycolipid Antibodies (Anti PGL-1) seropositivity, negative Mitsuda test, absence of Bacillus Calmette-Guérin (BCG) scar, positive Polymerase Chain Reaction (PCR) in blood; age and race; conviviality, education, contact time and type of contact, as well as elements related to the index case (bacilloscopic index; genetic conditions, family relationships), and some combined factors were shown to be relevant risk factors associated with the development of the disease in Brazilian leprosy contacts. The protective factors reported were the presence of one or more BCG scars, positive Mitsuda test, and education level. All selected studies were considered of high quality according to NOS. The knowledge of disease-related risk and protective factors provides the scientific basis for decision-making in the management of the disease in leprosy contact
local.publisher.countryBrasil
local.publisher.departmentMEDICINA - FACULDADE DE MEDICINA
local.publisher.initialsUFMG
local.url.externahttps://doi.org/10.1590/S1678-9946202264055

Arquivos

Pacote original

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
Factors associated with the development of leprosy in pdfa.pdf
Tamanho:
256.84 KB
Formato:
Adobe Portable Document Format
Baixar

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG