Oral manifestation of lymphomatoid granulomatosis
Carregando...
Data
Título da Revista
ISSN da Revista
Título de Volume
Editor
Universidade Federal de Minas Gerais
Descrição
Tipo
Artigo de periódico
Título alternativo
Primeiro orientador
Membros da banca
Resumo
Lymphomatoid granulomatosis (LYG) is a rare B-cell lymphoproliferative disorder driven by Esptein-Barr virus (EBV) that most commonly affects the lungs, although extra pulmonary sites like the central nervous system, skin, liver and kidney can also be involved. It is microscopically characterized by an angiocentric and angiodestructive growth pattern, predominantly composed by small T-cells, although a smaller population of atypical large B-cells is considered the true neoplastic component. Oral cavity involvement of LYG has rarely been described and the diagnosis of this neoplasm is very difficult. The aim of this report is to present a rare case of LYG affecting an 86-year-old female patient that was diagnosed due to an extensive, ulcerated and painful oral lesion affecting the hard palate. Detailed microscopic evaluation together with a large immunohistochemical study were necessary to achieve the correct diagnosis of LYG.
Abstract
Assunto
Lymphoma, Lymphomatoid granulomatosis, Mouth, Palate, Diagnosis, Immunohistochemistry, Epstein-Barr virus infections, Cells
Palavras-chave
Head and Neck Pathology, Oral manifestation of lymphomatoid granulomatosis busca dia 16 do 10 2023 assunto linfoma fao clinica restrito acess título periódico Head and neck pathology
Citação
Departamento
Curso
Endereço externo
https://link.springer.com/article/10.1007/s12105-018-0910-x