Mucosal leishmaniasis in brazilian patients: two case reports with similar clinical presentation and different approaches

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Resumo

Mucosal leishmaniasis is a chronic infection that affects the upper respiratory tract and/or the oral mucosa caused by Leishmania protozoan parasites. We present two cases of oral leishmaniasis and discuss the different diagnostic strategies and treatment. In both cases, the patients were male, 60 and 94 years of age, and presented with lesions on the soft palate. In the first patient, the final diagnosis was made on the basis of histopathologic examination. In the second case, polymerase chain reaction and Montenegro skin test were necessary to confirm the diagnosis. The first patient was treated with meglumine antimoniate (Glucantime), and the lesions healed after 2 months. In the second case, the patient received treatment with liposomal amphotericin B but later died as a result of generalized infection. Mucosal leishmaniasis is a highly disfiguring disease. Early diagnosis is important to prevent a lethal outcome.

Abstract

Assunto

Meglumine antimoniate, Leishmaniasis, Mouth mucosa, Amphotericin B, Therapeutics, Diagnosis, Leishmania

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Infectious diseases, leishmaniasis acesso restrito Maria Cassia Ferreira de Aguiar buscar essa professora Mucosal leishmaniasis in brazilian patients: two case reports with similar clinical presentation and different approaches data 23/07/2024 fao clinica

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https://www.sciencedirect.com/science/article/pii/S2212440316000882?via%3Dihub

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