Evolução clínica, ultrassonográfica e fatores de risco para lesão renal em crianças com Rim Único Congênito

Abstract

The main objective of this study was to describe the clinical course of children with a functioning congenital solitary kidney (CSU) who were followed up over the long term, assessing the evolution of renal function and ultrasonographic progression of the affected unit. In this retrospective cohort study, 162 patients with CSU were systematically followed up (median, 8.5 years). The primary outcome was the time until the occurrence of a composite event of renal injury, which includes proteinuria, hypertension and chronic kidney disease (CKD). A predictive model was developed. Considering the natural history of congenital solitary kidney, since the vast majority of these patients will survive until adulthood, it is expected that the results of this study can add to and contribute to the definition of an effective and evidence-based strategy for the approach to congenital solitary kidney.