Influence of oophorectomy on glycemia and lipidogram
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Universidade Federal de Minas Gerais
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Artigo de periódico
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Purpose: To verify the influence of oophorectomy on lipidogram and glycemia.Methods: Fifty six female rats were divided into the following 7 groups (n = 8): group 1 – sham group, group 2 – oophorectomy 30 days, group 3 – oophorectomy 35 days, group 4 – oophorectomy 40 days, group 5 – oophorectomy 45 days, group 6 – oophorectomy 70 days, group 7 – oophorectomy 55 days. Animals were following by number of days according the group. Was evaluated the serum levels of glucose and lipid profile.Results: The oophorectomized rats presented higher glycemia. Groups 3, 4, 6 and 7 had a higher glycemia and LDL levels (except for group 6) and groups 6 and 7 had lowest levels of HDL. Group 7 had highest level of VLDL than oophorectomy groups. There was no difference
in triglycerides levels.Conclusion: Oophorectomy was related to dyslipidemia and insulin resistance, mainly after 50th days
Abstract
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Ovariectomy, Climacteric, Dyslipidemias, Rats
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Ovariectomy, Climacteric, Dyslipidemias, Rats
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https://doi.org/10.1590/s0102-865020180050000003