Benign tumors of the peripheral nerve sheath: a retrospective study from an oral and maxillofacial pathology service

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dc.creatorAline Maria do Couto
dc.creatorDaniela Pereira Meirelles
dc.creatorLeni Verônica de Oliveira Silva
dc.creatorRicardo Alves Mesquita
dc.creatorLucas Guimarães Abreu
dc.creatorMaria Cássia Ferreira de Aguiar
dc.date.accessioned2024-08-21T21:28:35Z
dc.date.accessioned2025-09-09T00:44:32Z
dc.date.available2024-08-21T21:28:35Z
dc.date.issued2022-09
dc.identifier.doihttps://doi.org/10.1016/j.oooo.2022.01.592
dc.identifier.issn2212-4411
dc.identifier.urihttps://hdl.handle.net/1843/74607
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofOral Surgery Oral Medicine Oral Pathology Oral Radiology
dc.rightsAcesso Restrito
dc.subjectTongue
dc.subjectGingiva
dc.subjectNeurofibroma
dc.subjectNeurilemmoma
dc.subjectNeuroma
dc.subjectMouth mucosa
dc.subjectNeurofibromatoses
dc.titleBenign tumors of the peripheral nerve sheath: a retrospective study from an oral and maxillofacial pathology service
dc.typeArtigo de periódico
local.citation.epagee194
local.citation.issue3 Oral surgery oral medicine oral pathology oral radiology
local.citation.spagee194
local.citation.volume134
local.description.resumoObjectives To describe the main demographic and clinical characteristics of lesions with histopathologic diagnosis of benign tumor of the peripheral nerve sheath (BTPNS). Study Design The biopsy files from an oral and maxillofacial pathology service were assessed and cases with histopathologic diagnosis of neurofibroma, neurilemoma, or palisaded encapsulated neuroma (PEN) were selected. Results A total of 94 BTPNSs were diagnosed among 38119 biopsy specimens (0.25%). Of these, 58 were neurofibromas (61.7%). Most patients were female (61, 64.9%), with ages ranging from the second to the fourth decade (56, 59.6%). The main anatomic location affected by neurofibroma was gingiva (19, 32.8%). Neurilemomas were mainly located on the tongue (9, 37.5%) and PEN in the buccal mucosa (5, 41.7%). Most of the lesions had mucosa-like color (52, 55.3%) and median size of 15 mm and were painless (76, 80.9%). Among neurofibromas, 7 cases were associated with neurofibromatosis (12.1%). Conclusions The BTPNSs were uncommon diagnoses at the oral and maxillofacial pathology service. The lesions were mainly neurofibromas, affected women, had mucosa-like color, and had median lesion size larger than 1 cm. Some neurofibromas were associated with neurofibromatosis.
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/abs/pii/S2212440322006174#preview-section-abstract

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