AISI 304 stainless steel as a transducer substrate in electrochemical biosensors for medical applications
Carregando...
Data
Título da Revista
ISSN da Revista
Título de Volume
Editor
Universidade Federal de Minas Gerais
Descrição
Tipo
Artigo de periódico
Título alternativo
Primeiro orientador
Membros da banca
Resumo
Stainless Steels (SS) are promising candidates to constitute the transducer substrate of devices for electrochemical sensing mainly due to their high electrical conductivity, biocompatibility and relative low cost. In this study, the corrosion resistance of SS was examined in four solutions that represent the environment of biosensors in real applications: 0.01 M Tris buffer (pH 7.4), an electrolyte containing Tris and 0.1M KCl as supporting source of ions, Hanks’ solution to simulate body fluids and, also, a solution to represent the electrolyte commonly used to performed Cyclic Voltammetry (CV). Potentiodinamic anodic polarization, Chronoamperometry and images of Optical Microscopy revealed that the Hanks’ and CV solutions were the most aggressive media to the SS electrodes, which remained chemically stable in both Tris and electrolyte during 16h under the influence of critical potentials. When functionalized to recognize venom from Crotalus snakes, the SS suffered an increase of the diameter of the capacitive arc in the EIS experiment as a result of the detection of the target analyte, corroborating it is a promising electrochemical transducer for application in biosensors.
Abstract
Assunto
Ciência dos materiais, Biossensores, Aço inoxidável, Detectores eletroquímicos, Análise eletroquímica, Voltametria, Tecnologia médica, Aço - Corrosão
Palavras-chave
Biosensor, Stainless Steel, Transducer, Electrochemical Sensing
Citação
Curso
Endereço externo
https://biomedres.us/fulltexts/BJSTR.MS.ID.003117.php