Acetylcholinesterase Inhibitory Potential in Cinnamon Seed Oil (Cinnamomum zeylanicum Nees) Lauraceae from Roraima, Brazil

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dc.creatorRomulo Estevam Ribeiro Pedro
dc.creatorMoisés Felix de Carvalho Neto
dc.creatorAlves Chagas Edvan
dc.creatorPollyana C. Chagas
dc.creatorJacqueline Aparecida Takahashi
dc.creatorAna Cristina G. Reis de Melo
dc.creatorRicardo Carvalho Dos Santos
dc.creatorAntonio A. de Melo Filho
dc.date.accessioned2023-10-17T23:30:41Z
dc.date.accessioned2025-09-09T00:17:10Z
dc.date.available2023-10-17T23:30:41Z
dc.date.issued2019
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipFINEP - Financiadora de Estudos e Projetos, Financiadora de Estudos e Projetos
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.3303/CET1975061
dc.identifier.issn2283-9216
dc.identifier.urihttps://hdl.handle.net/1843/59572
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofChemical Engineering Transactions
dc.rightsAcesso Aberto
dc.subjectAlzheimer, Doença de
dc.subjectProdutos Naturais
dc.subject.otherFixed oil
dc.subject.otherBiological activity
dc.subject.otherNeurodegenerative diseases
dc.subject.otherAlzheimer
dc.subject.otherNatural products
dc.titleAcetylcholinesterase Inhibitory Potential in Cinnamon Seed Oil (Cinnamomum zeylanicum Nees) Lauraceae from Roraima, Brazil
dc.typeArtigo de periódico
local.citation.epage366
local.citation.spage361
local.citation.volume75
local.description.resumoOne of the oldest plants known and considered a symbol of wisdom in antiquity especially in China is cinnamon (Cinnamomum zeylanicum Nees). The objective of this work was to study the fixed oil extracted from cinnamon (Cinnamomum zeylanicum Nees) seeds regarding its biological potential for inhibition of acetylcholinesterase. The inhibitory activity test of hexane extract studied on the enzyme acetylcholinesterase was conducted based on Ellman spectrophotometric method. The percentage of acetylcholinesterase enzyme inhibition was 65.5%, being considered a potent inhibitor according to the literature standarts. In conclusion, the results indicate that the oil can be used in the pharmaceutical industry as part or to develop drugs for treatment of certain neurodegenerative diseases, such as Alzheimer's disease.
local.identifier.orcidhttps://orcid.org/0000-0002-8831-1609
local.publisher.countryBrasil
local.publisher.departmentICX - DEPARTAMENTO DE QUÍMICA
local.publisher.initialsUFMG
local.url.externahttps://www.aidic.it/cet/19/75/061.pdf

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