A multicenter study of malignant oral and maxillofacial lesions in children and adolescents
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Universidade Federal de Minas Gerais
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Artigo de periódico
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Objectives: To investigate the frequency of malignant oral and maxillofacial lesions among children and adolescents from representative geographic regions of Brazil.
Materials and methods: A retrospective study was conducted on biopsies obtained from 1990 to 2016 at six Brazilian oral and maxillofacial pathology referral centers. A total of 85,105 biopsy specimens from children and adolescents were analyzed. Gender, age, anatomical location, symptomatology and histopathological diagnosis were evaluated. Data were analyzed using descriptive statistical methods.
Results: Fifty-eight (0.06%) malignant oral and maxillofacial lesions were diagnosed in children (19%) and adolescents (81%). The lesions were more frequent among females (60.3%) and adolescents. The most prevalent lesions were mucoepidermoid carcinomas (22.4%), osteosarcomas (13.8%), squamous cell carcinomas (12.1%), and Burkitt's lymphomas (12.1%). The most commonly affected sites were the palate (19%), mandible (13.8%), and maxilla (13.8%). Almost half the patients were asymptomatic.
Conclusion: Pediatric oral and maxillofacial malignant lesions were infrequent and showed wide diversity, with a prevalence of mucoepidermoid carcinomas. Analysis of malignant lesions in children and adolescents helps pediatric dentists and oncologists to obtain a better understanding of such lesions and to reduce the time for diagnosis, with a consequent improvement of prognosis.
Abstract
Assunto
Epidemiology, Adolescent, Child, Neoplasms, Morbidity, Prevalence, Palate, Maxilla, Mandible, Carrier state, Evaluation study, Diagnosis, Prognosis
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Adolescent, Child, Epidemiology, Neoplasms, Oral lesions, Oral oncology
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https://www.sciencedirect.com/science/article/pii/S136883751730341X?via%3Dihub#ak005