Preemptive analgesia in dental implant surgery: a systematic review and meta-analysis of randomized controlled trials

Página do item simplificado
dc.creatorGustavo Henrique Mattos Pereira
dc.creatorCarolina Castro Martins
dc.creatorRafael Paschoal Esteves Lima
dc.creatorRaquel Alvarenga Brant
dc.creatorLuis Otavio de Miranda Cota
dc.creatorFernando de Oliveira Costa
dc.date.accessioned2024-06-20T17:56:47Z
dc.date.accessioned2025-09-09T01:07:41Z
dc.date.available2024-06-20T17:56:47Z
dc.date.issued2021-08-19
dc.identifier.doihttps://doi.org/10.4317%2Fmedoral.24639
dc.identifier.issn1698-6946
dc.identifier.urihttps://hdl.handle.net/1843/69318
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofMedicina Oral, Patología Oral y Cirugía Bucal
dc.rightsAcesso Aberto
dc.subjectPain, postoperative
dc.subjectSystematic review
dc.subjectAnalgesia
dc.subjectSurgery, oral
dc.subjectDental implants
dc.subjectNetwork meta-analysis
dc.subject.otherpreemptive analgesia
dc.subject.otherIMPLANT
dc.subject.otherperiodontal surgical
dc.subject.otherMedicina oral, patología oral y cirugía bucal (ed. impresa)
dc.titlePreemptive analgesia in dental implant surgery: a systematic review and meta-analysis of randomized controlled trials
dc.typeArtigo de periódico
local.citation.epagee10
local.citation.issue5
local.citation.spagee1
local.citation.volume26
local.description.resumoBackground To assess the effectiveness of preemptive analgesia in dental implant surgery in randomized controlled trials (RCTs). Material and Methods The present study was conducted in accordance with the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and registered in PROSPERO database CRD42020168757. A search without restrictions regarding language or date of publication was conducted in six databases and gray literature. A random effect meta-analysis compared the efficacy of preemptive analgesia compared to placebo through pooled OR and 95%CI. The interpretation of results followed the certainty of evidence using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach together with the magnitude of the effect according to GRADE guidelines. Results Four studies were included in the review and three were incorporated into the meta-analysis. All studies demonstrated that preemptive analgesia contributed to a significant improvement in the postoperative pain control. However, the overall pooled standard mean difference (SMD) showed that preemptive analgesia had small effects compared to placebo in reducing pain (SMD: -0.45; IC: -0.83; -0.08) with low certainty of the evidence. Our meta-analysis showed that the magnitude of the effect was bigger six to eight hours after the surgery (large effect), compared to the time of one to two hours after the surgery (small effect). Conclusions Preemptive analgesia may have a positive effect in reducing pain compared to not using preemptive medication, but the evidence is very uncertain.
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA
local.publisher.initialsUFMG
local.url.externahttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412441/

Arquivos

Pacote original

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
Preemptive analgesia in dental implant surgery a systematic review and meta-analysis of randomized controlled trials.pdf
Tamanho:
1.59 MB
Formato:
Adobe Portable Document Format
Baixar

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG