Bleaching gel mixed with MI paste plus reduces penetration of H2O2 and damage to pulp tissue and maintains bleaching effectiveness

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dc.creatorJéssica Galbiati Barbosa
dc.creatorFrancine Benetti
dc.creatorMarjorie de Oliveira Gallinari
dc.creatorMarina Carminatti
dc.creatorAnna Beatriz Dias da Silva
dc.creatorIsabela Nakahara Ikeda Lopes
dc.creatorAndré Luiz Fraga Briso
dc.creatorLuciano Tavares Ângelo Cintra
dc.date.accessioned2022-11-28T13:22:36Z
dc.date.accessioned2025-09-08T22:48:55Z
dc.date.available2022-11-28T13:22:36Z
dc.date.issued2019-07-13
dc.description.sponsorshipFAPESP - Fundação de Amparo à Pesquisa do Estado de São Paulo
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1007/s00784-019-03009-5
dc.identifier.issn14326981
dc.identifier.urihttps://hdl.handle.net/1843/47499
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofClinical Oral Investigations
dc.rightsAcesso Restrito
dc.subjectTooth bleaching
dc.subjectHydrogen peroxide
dc.subjectMolar
dc.subjectDentin
dc.subject.otherCasein phosphopeptide-amorphous calcium phosphate (CPP-ACP);
dc.subject.otherDental bleaching
dc.subject.otherHydrogen peroxide
dc.subject.otherMI Paste Plus
dc.subject.otherPulp inflammation
dc.titleBleaching gel mixed with MI paste plus reduces penetration of H2O2 and damage to pulp tissue and maintains bleaching effectiveness
dc.typeArtigo de periódico
local.citation.epage1309
local.citation.issue3
local.citation.spage1299
local.citation.volume24
local.description.resumoObjectives: MI Paste Plus remineralizer (Rem) strengthens dental structures after bleaching. We investigated the effect of Rem on the penetration of hydrogen peroxide (H2O2), bleaching effectiveness, and pulp inflammation after bleaching. Materials and methods: Bovine disks were grouped as follows (n = 10): control (untreated), bleached (Ble; 35% H2O2, 30 min), Ble-Rem (H2O2 followed by Rem, 30 min), Rem-Ble (Rem followed by H2O2), Rem-Ble-Rem (Rem before and after H2O2), and Ble+Rem (mixture of Rem with H2O2, 1:1, 30 min). The penetration of H2O2 was quantified and bleaching efficacy was analyzed. Upper rat molars (n = 10) received the same treatments at random. The rats were euthanized after two days and 30 days, and their jaws were removed for histological analysis. Statistical tests were performed (P < 0.05). Results: The bleached groups, except Ble+Rem (P > 0.05), showed significant H2O2 penetration compared with control (P < 0.05). Color alteration analysis showed that ΔL and ΔE were significantly higher in the bleached groups than those in control (P < 0.05); the Δb of the bleached groups differed from that of control at 24 h (P < 0.05). At two days, necrosis or inflammation was observed in the bleached groups compared with control (P < 0.05), except Ble+Rem, which was similar to control (P > 0.05). At 30 days, tertiary dentin formation was significant in the bleached groups (P < 0.05), except Ble+Rem (P > 0.05). Conclusion: The mixture of MI Paste Plus and bleaching gel reduces H2O2 penetration and pulp damage and maintains bleaching effectiveness. Clinical relevance: Because bleaching can damage dental tissues, we studied a new bleaching protocol that reduces damage to the pulp tissue while maintaining bleaching efficiency: a single application of 30 min of MI Paste Plus mixed with 35% H2O2 bleaching gel (1:1)
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORA
local.publisher.initialsUFMG
local.url.externahttps://link.springer.com/article/10.1007/s00784-019-03009-5

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