Ameloblastic fibroma and ameloblastic fibrosarcoma: a systematic review

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dc.creatorBruno Ramos Chrcanovic
dc.creatorPeter A. Brennan
dc.creatorSiavash Rahimi
dc.creatorRicardo Santiago Gomez
dc.date.accessioned2024-12-17T20:19:03Z
dc.date.accessioned2025-09-08T22:56:43Z
dc.date.available2024-12-17T20:19:03Z
dc.date.issued2018-04
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1111/jop.12622
dc.identifier.issn1600-0714
dc.identifier.urihttps://hdl.handle.net/1843/78740
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJournal of Oral Pathology & Medicine
dc.rightsAcesso Restrito
dc.subjectMargins of excision
dc.subjectRecurrence
dc.subjectClinical study
dc.subjectRadiology
dc.subjectProbability
dc.subjectWounds and injuries
dc.subject.otherAmeloblastic fibroma
dc.subject.otherAmeloblastic fibrosarcoma
dc.subject.otherClinical features
dc.subject.otherOdontogenic tumours
dc.subject.otherRecurrence rate
dc.titleAmeloblastic fibroma and ameloblastic fibrosarcoma: a systematic review
dc.typeArtigo de periódico
local.citation.epage325
local.citation.issue4
local.citation.spage315
local.citation.volume47
local.description.resumoPurpose: To integrate the available data published to date on ameloblastic fibromas (AF) and ameloblastic fibrosarcomas (AFS) into a comprehensive analysis of their clinical/radiological features. Methods: An electronic search was undertaken in July 2017. Eligibility criteria included publications having enough clinical, radiological and histological information to confirm a definite diagnosis. Results: A total of 244 publications (279 central AF tumours, 10 peripheral AF, 103 AFS) were included. AF and AFS differed significantly with regard to the occurrence of patients' mean age, bone expansion, cortical bone perforation and lesion size. Recurrence rates were as follows: central AF (19.2%), peripheral AF (12.5%), AFS (all lesions, 35%), primary (de novo) AFS (28.8%) and secondary AFS (occurring after an AF, 50%). Larger lesions and older patients were more often treated by surgical resections for central AF. Segmental resection resulted in the lowest rate of recurrence for most of the lesion types. AFS treated by segmental resection had a 70.5% lower probability to recur (OR 0.295; P = .049) than marginal resection; 21.3% of the AFS patients died due to complications related to the lesion. Conclusions: Very long follow-up is recommended for AF lesions, due to the risk of recurrence and malignant change into AFS. Segmental resection is the most recommended therapy for AFS.
local.identifier.orcidhttps://orcid.org/0000-0002-3460-3374
local.identifier.orcidhttps://orcid.org/0000-0003-4804-3264
local.identifier.orcidhttps://orcid.org/0000-0002-8282-1480
local.identifier.orcidhttps://orcid.org/0000-0001-8770-8009
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://onlinelibrary.wiley.com/doi/10.1111/jop.12622

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