Revisiting the chronic renal disease in pediatric patients
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Universidade Federal de Minas Gerais
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Artigo de periódico
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Membros da banca
Resumo
This paper aims to review the diagnosis, epidemiological data, etiology, pathophysiology and progression of Chronic Kidney Disease (CKD), with emphasis on pediatric patients. CKD is defined as a group of structural and functional kidney abnormalities observed for more than three months, which affects patient's health. CKD prevalence in children is lower than in adults, but is associated to cardiovascular diseases and has high mortality and morbidity rates. CKD-affected children have alterations in physical and psychological development, growth retardation and muscle weakness, among other complications which decrease patients’ quality of life. The main causes of CKD in children are congenital anomalies of the kidney and urinary tract, and primary glomerulopathy, especially focal segmental glomerulosclerosis. Some conditions contribute to CKD progression, such as responsiveness to treatment. The knowledge of the pathophysiology of CKD and disease progression mechanisms is important for the early treatment and to predict the clinical evolution, aiming to provide counseling to families and to slow the progression of kidney disease to an end stage.
Abstract
Assunto
Insuficiência renal crônica, Pediatria, Prevalência
Palavras-chave
Chronic kidney disease, Pediatrics, Etiology, Prevalence, Progression
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Endereço externo
https://www.ijhsr.org/archive_ijhsr_vol.6_issue8.html