Recurrence probability for keratocystic odontogenic tumors: an analysis of 6427 cases

Página do item simplificado
dc.creatorBruno Ramos Chrcanovic
dc.creatorRicardo Santiago Gomez
dc.date.accessioned2024-12-11T21:03:36Z
dc.date.accessioned2025-09-09T00:43:42Z
dc.date.available2024-12-11T21:03:36Z
dc.date.issued2017
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1016/j.jcms.2016.11.010
dc.identifier.issn1878-4119
dc.identifier.urihttps://hdl.handle.net/1843/78611
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJournal of Cranio-Maxillofacial Surgery
dc.rightsAcesso Restrito
dc.subjectMeta-analysis
dc.subjectOutcome assessment, health care
dc.subjectMargins of excision
dc.subjectRisk
dc.subjectRecurrence
dc.subjectProbability
dc.subject.otherEnucleation
dc.subject.otherKeratocystic odontogenic tumor
dc.subject.otherMarsupialization
dc.subject.otherMeta-analysis
dc.subject.otherOutcome
dc.subject.otherResection
dc.titleRecurrence probability for keratocystic odontogenic tumors: an analysis of 6427 cases
dc.typeArtigo de periódico
local.citation.epage251
local.citation.issue2
local.citation.spage244
local.citation.volume45
local.description.resumoPurpose: To investigate and compare the probability of recurrence of keratocystic odontogenic tumors (KCOTs) for different variables and treatment protocols. Materials and methods: An electronic search was undertaken in April 2016 that included clinical series of KCOTs reporting recurrences. Untransformed proportions and meta-analyses were performed to estimate the probability/risk of recurrence, according to several variables. Results: A total of 94 publications were included (6427 KCOTs, 1464 recurrences). Probability of recurrence: all lesions, 21.1%; nevoid basal cell carcinoma syndrome, 35.4%; males, 20.3%; females, 19.3%; maxilla, 15.3%; mandible, 21.5%; unilocular, 14.7%; multilocular, 24.4%; marsupialization/decompression, 28.7%; decompression + enucleation ± additional therapy, 18.6%; enucleation/curettage, 22.5%; enucleation + peripheral ostectomy, 18.6%; enucleation + Carnoy's solution, 5.3%; enucleation + cryotherapy, 20.9%; marginal/segmental resection, 2.2%. The recurrence was not statistically significantly affected by lesion location (maxilla vs. mandible, risk ratio [RR] 0.92, P = 0.32) or patient's sex (male vs. female, RR 0.94, P = 0.44), but by locularity (unilocular vs. multilocular, RR 0.67, P = 0.007). Recurrence risk for surgical managements: marsupialization vs. enucleation (RR 1.65, P = 0.0006), marsupialization vs. resection (RR 3.17, P = 0.009), enucleation alone vs. enucleation + peripheral ostectomy (RR 1.66, P = 0.05), enucleation alone vs. enucleation + Carnoy's solution (RR 1.94, P = 0.03), enucleation alone vs. enucleation + cryotherapy (RR 0.88, P = 0.56). Conclusions: KCOTs have a considerable rate of recurrence, which varies significantly according to some clinical, radiographic, and histopathological features, as well as surgical management.
local.identifier.orcidhttps://orcid.org/0000-0002-3460-3374
local.identifier.orcidhttps://orcid.org/0000-0001-8770-8009
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S1010518216302852?via%3Dihub#sec7

Arquivos

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG