Oral melanoma involving gingiva and palate
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Universidade Federal de Minas Gerais
Descrição
Tipo
Artigo de periódico
Título alternativo
Primeiro orientador
Membros da banca
Resumo
A67-year-old male farmer presented with the complaint of a
slightly symptomatic spot in the mouth for the past 2 years. The
medical history discussed no abnormalities. Extraoral examina
tion revealed cervical lymphadenopathy on the left side and
intraoral examination a blue-black sessile elevated mass with
irregular borders, involving the attached vestibular gingiva of
teeth 27 and 28, extending to the hard palate and measuring
approximately 3.5 cm. Panoramic radiograph did not show bone
involvement. A diagnostic hypothesis of oral melanoma was
made, and an incisional biopsy was performed. Microscopic find
ings revealed a proliferation of densely pigmented pleomorphic
cells, invading the subepithelial connective tissue in sheets or
nests in an organoid fashion. Immunopositivity for S-100, Melan
A, and HMB-45 confirmed the diagnosis of melanoma. The
patient was referred to an oncology hospital, and, unfortunately,
we have no information if he initiated the treatment.
Abstract
Assunto
Melanoma, Cell proliferation, Pigmentation, Connective tissue, Mouth, Lymphadenopathy, Manipulation, spinal, Gingiva, Tooth, Palate, hard
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Endereço externo
https://www.sciencedirect.com/science/article/pii/S2212440319310120