Determining performance parameters in qualitative multivariate methods using probability of detection (POD) curves. Case study: two common milk adulterants

Página do item simplificado
dc.creatorCarina de Souza Gondim
dc.creatorRoberto Gonçalves Junqueira
dc.creatorScheilla Vitorino Carvalho de Souza
dc.creatorMaria Pilar Callao
dc.creatorItziar Ruisánchez
dc.date.accessioned2022-05-06T21:03:36Z
dc.date.accessioned2025-09-09T01:18:51Z
dc.date.available2022-05-06T21:03:36Z
dc.date.issued2017-06-01
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.description.sponsorshipOutra Agência
dc.identifier.doi10.1016/j.talanta.2016.12.065
dc.identifier.issn0039-9140
dc.identifier.urihttps://hdl.handle.net/1843/41439
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofTalanta
dc.rightsAcesso Restrito
dc.subjectTecnologia de alimentos
dc.subjectLeite
dc.subject.otherMethod validation
dc.subject.otherMultivariate qualitative analysis
dc.subject.otherMilk adulteration
dc.subject.otherPOD curves
dc.subject.otherPerformance parameters
dc.subject.otherSIMCA
dc.titleDetermining performance parameters in qualitative multivariate methods using probability of detection (POD) curves. Case study: two common milk adulterants
dc.typeArtigo de periódico
local.citation.epage30
local.citation.spage23
local.citation.volume168
local.description.resumoA strategy for determining performance parameters of two–class multivariate qualitative methods was proposed. As case study, multivariate classification methods based on mid-infrared (MIR) spectroscopy coupled with the soft independent modelling of class analogy (SIMCA) technique for detection of hydrogen peroxide and formaldehyde in milk were developed. From the outputs (positive/negative/inconclusive) of the samples, which were unadulterated and adulterated at target value, the main performance parameters were obtained. Sensitivity and specificity values for the unadulterated and adulterated classes were satisfactory. Inconclusive ratios 12% and 21%, respectively, for hydrogen peroxide and formaldehyde were obtained. To evaluate the performance parameters related to concentration, Probability of Detection (POD) curves were established, estimating the decision limit, the capacity of detection and the unreliability region. When inconclusive outputs were obtained, two additional concentration limits were defined: the decision limit with inconclusive outputs and the detection capability with inconclusive outputs. The POD curves showed that for concentrations below 3.7 g L−1 of hydrogen peroxide and close to zero of formaldehyde, the chance of giving a positive output (adulterated sample) was lower than 5%. For concentrations at or above 11.3 g L−1 of hydrogen peroxide and 10 mg L−1 of formaldehyde, the probability of giving a negative output was also lower than 5%.
local.publisher.countryBrasil
local.publisher.departmentFAR - DEPARTAMENTO DE ALIMENTOS
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S0039914016310128?via%3Dihub

Arquivos

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG