The health-related quality of life in patients with chagas disease: the state of the art

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dc.creatorIgor Lucas Geraldo Izalino de Almeida
dc.creatorAna Thereza Chaves Lages
dc.creatorMauro Felippe Felix Mediano
dc.creatorManoel Otávio da Costa Rocha
dc.creatorHenrique Silveira Costa
dc.creatorLuciano Fonseca Lemos de Oliveira
dc.creatorPedro Henrique Scheidt Figueiredo
dc.creatorRafael Dias de Brito Oliveira
dc.creatorThayrine Rosa Damasceno
dc.creatorWhesley Tanor Silva
dc.creatorLucas Frois Fernandes de Oliveira
dc.creatorMatheus Ribeiro Ávila
dc.creatorVanessa Pereira Lima
dc.date.accessioned2024-01-11T19:57:56Z
dc.date.accessioned2025-09-08T23:19:55Z
dc.date.available2024-01-11T19:57:56Z
dc.date.issued2022
dc.format.mimetypepdf
dc.identifier.doi10.1590/0037-8682-0657-2021
dc.identifier.issn16789849
dc.identifier.urihttps://hdl.handle.net/1843/62646
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofRevista da Sociedade Brasileira de Medicina Tropical
dc.rightsAcesso Aberto
dc.subjectChagas disease
dc.subjectChagas cardiomyopathy
dc.subjectQuality of life
dc.subject.otherChagas disease
dc.subject.otherChagas cardiomyopathy
dc.subject.otherQuality of life
dc.titleThe health-related quality of life in patients with chagas disease: the state of the art
dc.typeArtigo de periódico
local.citation.epage10
local.citation.issuee0657-2021
local.citation.spage1
local.citation.volume55
local.description.resumoChagas disease (CD) is a neglected tropical disease associated with poverty in which patients are surrounded by stigma. These factors can contribute to reducing health-related quality of life (HRQoL). Therefore, a broad discussion of HRQoL in the CD population is required. This study aimed to discuss the main findings of HRQoL in patients with CD, focusing on the association between sociodemographic and lifestyle factors, echocardiographic and functional determinants, and the effect of non-invasive interventions on HRQoL. A literature search of the MEDLINE, Web of Science, CINAHL, Scopus, and LILACS databases was performed with no data or language restrictions. Twenty-two articles were included in this meta-analysis. In general, HRQoL is worse in patients with CD than in healthy individuals, particularly in the presence of cardiovascular and/or gastrointestinal symptoms. Sex, age, functional class, level of physical activity, healthy habits, and medications received could affect HRQoL. Among the echocardiographic and functional determinants, decreased systolic function seems to negatively affect HRQoL. No association with the peak oxygen uptake was observed in the maximal tests. By contrast, well-tolerated field tests with submaximal intensities were associated with HRQoL. Both pharmaceutical care and exercise training have a positive effect on the HRQoL of patients with Chagas cardiomyopathy, and the mental component can be a prognostic marker in this population. In conclusion, assessment of HRQoL can provide important information about the health status of patients with CD, and its use in clinical practice is warranted.
local.publisher.countryBrasil
local.publisher.departmentEEF - DEPARTAMENTO DE FISIOTERAPIA
local.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICA
local.publisher.initialsUFMG
local.url.externahttps://doi.org/10.1590/0037-8682-0657-2021

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