Ventilação não invasiva após extubação de recém-nascidos pré-termo

Abstract

Non-invasive ventilation has been used in preterm newborn with respiratory distress syndrome in an attempt to help the success of extubation. We investigated the success of extubation in infants less than or equal to 34 weeks gestational age and weight of 500g to less than or equal to 1500 grams . Neonates were randomized to non-invasive modalities support . 101 newborns, NIPPV (n=36) were included, bubble NCPAP (n=33) and respirator NCPAP (n=32). Sample evaluated the success rate was 81,8 % (n = 81) and the failure rate was 19,2% (n=20), the periintraventricular bleeding was lower in the group bubble NCPAP n=3 (9,1 %) p 0,03, the settings of the respirator before extubation, statistical significance was found for respiratory rate (p 0,04), but no clinical significance. About 70 % of the sample that failed were male.When the sample of the newborns that failed was compared with duration of mechanical ventilation and bronchopulmonary dysplasia, significant difference was observed. The extubation failure was related to bronchopulmonary dysplasia and duration of mechanical ventilation.The study showed a high rate of successful extubation and clinical importance of the modalities studied.