Effect of photodynamic therapy as an adjuvant to non-surgical periodontal therapy: periodontal and metabolic evaluation in patients with type 2 diabetes mellitus

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dc.creatorFlávia Isabelabarbosa
dc.creatorPatrícia Valente Araújo
dc.creatorLucas José Campos Machado
dc.creatorCláudia Silami Magalhães
dc.creatorMilena Maria Moreira Guimarães
dc.creatorAllyson Nogueira Moreira
dc.date.accessioned2023-07-24T20:18:55Z
dc.date.accessioned2025-10-03T19:11:19Z
dc.date.available2023-07-24T20:18:55Z
dc.date.issued2018-04-27
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1016/j.pdpdt.2018.04.013
dc.identifier.issn15721000
dc.identifier.urihttps://hdl.handle.net/1843/56914
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofPhotodiagnosis and Photodynamic Therapy
dc.rightsAcesso Restrito
dc.subjectDiabetes Mellitus
dc.subjectDoenças Periodontais
dc.subjectFotoquimioterapia
dc.subject.otherDiabetes mellitus
dc.subject.otherPeriodontal disease
dc.subject.otherPhotodynamic therapy
dc.titleEffect of photodynamic therapy as an adjuvant to non-surgical periodontal therapy: periodontal and metabolic evaluation in patients with type 2 diabetes mellitus
dc.typeArtigo de periódico
local.citation.epage250
local.citation.spage245
local.citation.volume22
local.description.resumoBackground: This pilot study aimed to evaluate the effect of antimicrobial photodynamic therapy (aPDT) as an adjuvant to non-surgical periodontal therapy (NSPT) on periodontal status and glycemic control in patients with type 2 diabetes mellitus and generalized chronic periodontitis. Methods: Twelve patients were evaluated at five time points: during the preparation of the patient (T0), during the treatment phase (T1) and after 30 (T2), 90 (T3) and 180 (T4) days. The patients had a mean age of 52.2 years and a 9.58-year history of diabetes, on average, and were divided into two randomized treatment groups: 6 patients received NSPT combined with aPDT (G1) and 6 patients received only NSPT (G2). The aPDT was applied associating the photosensitizing agent methylene blue (10 mg/ ml) with a red laser (660 nm–40 mW). The total time of exposure was 2 min per tooth.Results: Whitin the limitation of this study, the results showed that the plaque index reduced significantly only in the control group (p = 0.02) at T2 (30 days). For bleeding on probing, both groups showed a significant re duction between T1 and T2, with no difference between groups G1 and G2. Regarding the probing depth, there were no differences between groups, but the parameters decreased over time when compared to T1. The glycated haemoglobin and fructosamine levels did not significantly differ between or within the groups at any time point. Conclusion: When NSPT was combined with aPDT, no additional benefits were observed for the periodontal and metabolic clinical parameters
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORA
local.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/abs/pii/S1572100017304507?via%3Dihub

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