Oral and maxillofacial manifestations of chronic kidney disease-mineral and bone disorder: a multicenter retrospective study

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dc.creatorFlávia Sirotheau Corrêa Pontes
dc.creatorWladimir Gushiken de Campos
dc.creatorMilena Coelho Fernandes Caldato
dc.creatorRegina Matsunaga Martin
dc.creatorFelipe Paiva Fonseca
dc.creatorHélder Antônio Rebelo Pontes
dc.creatorMárcio Ajudarte Lopes
dc.creatorLucas Lacerda de Souza
dc.creatorDiogo Rezende
dc.creatorAlan Roger dos Santos-Silva
dc.creatorJacks Jorge
dc.creatorWagner Gomes da Silva
dc.creatorFábio Ramôa Pires
dc.creatorAndré Caroli Rocha
dc.date.accessioned2023-10-25T19:14:58Z
dc.date.accessioned2025-09-09T00:06:50Z
dc.date.available2023-10-25T19:14:58Z
dc.date.issued2018-01
dc.identifier.doihttps://doi.org/10.1016/j.oooo.2017.09.011
dc.identifier.issn22124403
dc.identifier.urihttps://hdl.handle.net/1843/60026
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofOral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
dc.rightsAcesso Restrito
dc.subjectChronic kidney disease-mineral and bone disorder
dc.subjectMouth
dc.subjectMaxilla
dc.subjectFace
dc.subjectMandible
dc.subjectDisease
dc.subject.otheracess restrito Oral and maxillofacial manifestations of chronic kidney disease-mineral and bone disorder: a multicenter retrospective study fao clinica busca dia 12 do 09 2023 assunto tumor
dc.titleOral and maxillofacial manifestations of chronic kidney disease-mineral and bone disorder: a multicenter retrospective study
dc.typeArtigo de periódico
local.citation.epage43
local.citation.spage31
local.citation.volume125
local.description.resumoObjective: To describe the oral and maxillofacial manifestations of patients diagnosed with chronic kidney disease-mineral and bone disorders. Study design: Over a 13-year period, clinicopathologic data of patients diagnosed with CKD-MBD who had oral and maxillofacial alterations were retrieved from the files of 4 Brazilian institutions. Data included clinical, radiographic, microscopic, and biochemical findings; treatment employed; and follow-up status. Results: Twenty-one cases were identified, with 13 patients diagnosed as brown tumor of hyperparathyroidism (BTH) and 8 as osteitis fibrosa/renal osteodystrophy (OF/RO) (4 of them clinically consistent with Sagliker syndrome). The mean age was 32.7 years, and the mandible was the most affected site (42.8%). OF/RO had an ill-defined "ground glass" radiographic appearance, and BTH produced well-defined radiolucent images. Biochemically the following mean values were obtained: parathormone 1511.07 pg/mL, calcium 9.25 mg/dL, phosphorus 5.19 mg/dL, alkaline phosphatase 941.55 U/L, urea 125.42 mg/dL, and creatinine 7.14 mg/dL. Treatment comprised vitamin D and calcium intake, parathyroidectomy, hemodialysis, renal transplantation, and local surgery. During follow-up, 5 patients with BTH were free of lesions, whereas 2 affected by OF/RO/Sagliker syndrome died. Conclusions: Oral and maxillofacial manifestations of BTH and OF/RO are uncommon, but they can be associated with an important life-threatening scenario
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S2212440317310672?via%3Dihub

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